Results 41 to 50 of about 12,185 (310)

Life Beyond Distributed Transactions on the Edge [PDF]

open access: yesProceedings of the 1st Workshop on Middleware for Edge Clouds & Cloudlets - MECC '16, 2016
Edge/Fog Computing is an extension to the Cloud Computing model, primarily proposed to pull some of the load on cloud data center towards the edge of the network, i.e., closer to the clients. Despite being a promising model, the foundations to adopt and fully exploit the edge model are yet to be clear, and thus new ideas are continuously advocated.
Shoker, Ali   +3 more
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Service Virtualization Using a Non-von Neumann Parallel, Distributed, and Scalable Computing Model

open access: yesJournal of Computer Networks and Communications, 2012
This paper describes a prototype implementing a high degree of transaction resilience in distributed software systems using a non-von Neumann computing model exploiting parallelism in computing nodes.
Rao Mikkilineni   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

State of the art and future research on distributed processing system in Internet environment

open access: yes大数据, 2018
Due to the gradual failure of Moore’s law,traditional centralized data processing systems begin to show performance bottlenecks,which can’t effectively support the rapid development of current business.At the same time,due to the security,cost,policy and
Pengwei MA, Kai WEI, Chunyu JIANG
doaj  

Local, Global, and Saga Transactions for SOA Services and Microservices (∗Services)

open access: yesIEEE Access
Transactions are a key issue in enterprise applications. Considering SOA and microservices as some of the most prevalent solutions for enterprise applications, transaction management differs significantly between these two solutions.
Antonio Navarro
doaj   +1 more source

Intelligent transaction: definition, modes, and research directions [PDF]

open access: yesInternational Journal of Crowd Science, 2019
Purpose - In the crowd intelligence networking era, the smart connections of human, machines and things enable point-to-point trustable transactions and distributed efficient collaboration; the smart connections among government, enterprises ...
Leiju Qiu   +4 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Distributed Power Trading Mechanism Based on Blockchain Smart Contracts

open access: yesEnergies
To address the challenges of inefficiency, vulnerability to attacks, and the lack of transparency and fairness in distributed power trading, a distributed power trading mechanism based on blockchain smart contracts is proposed.
Lihua Zhang   +4 more
doaj   +1 more source

Research on Data Transaction Security Based on Blockchain

open access: yesInformation, 2022
With the increasing value of various kinds of data in the era of big data, the demand of different subjects for data transactions has become more and more urgent. In this paper, a blockchain-based data transaction protection scheme is proposed to realize
Yongbo Jiang, Gongxue Sun, Tao Feng
doaj   +1 more source

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