Results 51 to 60 of about 12,185 (310)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
FEBS Open Bio, EarlyView.The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source
Blockchain-Based Transaction Validation Protocol for a Secure Distributed IoT Network
IEEE Access, 2020 Blockchain is attracting more and more attention to its applicability in the fields of Internet of Things (IoT). In particular, it is able to store data in unalterable blocks, associated with its secure peer-to-peer in a growing problem of transaction ...
A. S. M. Sanwar Hosen +6 more
doaj +1 more source
Zhongguo dianli, 2021 Promoting distributed generation to participate in power market transaction is the inevitable requirement of energy development and market development, while the distributed generation can participate in the market through the agent of electricity ...
Jingqing LIU +5 more
doaj +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
FEBS Open Bio, EarlyView.The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi +2 more
wiley +1 more source
Harp: optimization algorithm for cross-domain distributed transactions
大数据, 2023 The paradigm of near-data computing has driven banks and securities firms to build multiple data centers globally or nationally.In the traditional business model, transactions focused on accessing data within a single data center.With the changing ...
Qiyu ZHUANG +3 more
doaj
Toward a General Distributed Messaging Framework for Online Transaction Processing Applications
IEEE Access, 2017 This paper presents a general distributed messaging framework for online transaction processing applications in e-business industry, and we name it as Metamorphosis (MetaQ).
Jianwei Liao +3 more
doaj +1 more source
IEEE Access, 2020 In view of the problems of large-grid-level centralized transactions and dispatch centers with information asymmetry and high processing costs, a completely decentralized transaction architecture and a weak centralized scheduling strategy based on block ...
Xiaolin Fu, Hong Wang, Zhijie Wang
doaj +1 more source
Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen +47 more
wiley +1 more source
Distributed Transactions: Dissecting the Nightmare
, 2018 Many distributed storage systems are transactional and a lot of work has been devoted to optimizing their performance, especially the performance of read-only transactions that are considered the most frequent in practice. Yet, the results obtained so far are rather disappointing, and some of the design decisions seem contrived.
Didona, Diego +3 more
openaire +2 more sources