Results 71 to 80 of about 365,507 (334)

Design of distributed energy trading system based on cloud edge collaboration and blockchain

电力工程技术, 2023
The wide distributed energy has been the focus of power market. However, the traditional power trading platform cannot meet the high efficiency, flexibility, security and reliability requirements of the large-scale distributed energy transactions.
MA Guang, JIANG Wei, LI Wenchao, NIE Yongquan, SUN Chao   +4 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

DAG-Based Distributed Ledger for Low-Latency Smart Grid Network

Energies, 2019
In this paper, we propose a scheme that implements a Distributed Ledger Technology (DLT) based on Directed Acyclic Graph (DAG) to generate, validate, and confirm the electricity transaction in Smart Grid. The convergence of the Smart Grid and distributed
Seongjoon Park, Hwangnam Kim
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

A Blockchain Consensus Mechanism to Optimize Reputation-Based Distributed Energy Trading in Urban Energy System

IEEE Access
In modern cities, consumers with distributed energy resources (DERs) can trade energy by managing their consumption and supply. Blockchain is considered to provide technical support for establishing a distributed energy market, while the current ...
Chen Zhao, Dong Han, Chao Li, Han Wang
doaj   +1 more source

On transaction parallelizability in Ethereum [PDF]

arXiv, 2019
Ethereum clients execute transactions in a sequential order prescribed by the consensus protocol. This is a safe and conservative approach to blockchain transaction processing which forgoes running transactions in parallel even when doing so would be beneficial and safe, e.g., when there is no intersection in the sets of accounts that the transactions ...
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

An Algebraic-Topological Approach to Processing Cross-Blockchain Transactions [PDF]

arXiv, 2020
The state-of-the-art techniques for processing cross-blockchain transactions take a simple centralized approach: when the assets on blockchain $X$, say $X$-coins, are exchanged with the assets on blockchain $Y$---the $Y$-coins, those $X$-coins need to be exchanged to a "middle" medium (such as Bitcoin) that is then exchanged to $Y$-coins.
arxiv  

Warp: Lightweight Multi-Key Transactions for Key-Value Stores [PDF]

arXiv, 2015
Traditional NoSQL systems scale by sharding data across multiple servers and by performing each operation on a small number of servers. Because transactions on multiple keys necessarily require coordination across multiple servers, NoSQL systems often explicitly avoid making transactional guarantees in order to avoid such coordination.
arxiv  

TransNFV: Integrating Transactional Semantics for Efficient State Management in Virtual Network Functions [PDF]

arXiv, 2023
Managing shared mutable states in high concurrency state access operations is a persistent challenge in Network Functions Virtualization (NFV). This is particularly true when striving to meet chain output equivalence (COE) requirements. This paper presents TransNFV, an innovative NFV framework that incorporates transactional semantics to optimize NFV ...
arxiv