Results 91 to 100 of about 4,447,981 (197)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Functional Distribution, Capital Accumulation and Growth in a Non-Linear Macrodynamic Model

open access: yes, 2009
The article develops a macrodynamic model of income distribution, capital accumulation, and growth in which investment is nonlinear in distribution: at intermediate and high (low) levels of wage share, the impact of a higher profit share on investment ...
Lima, Gilberto Tadeu
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Cambridge Distribution in a World Economy

open access: yes, 1999
The article outlines a two-country Cambridge model of growth and distribution. The condition for the Cambridge equation to apply to the world economy is outlined.
O’Connell, Joan
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The mode-based decomposition into the growth and distribution effects for segments of poor

open access: yes
This study proposes the mode-based decomposition approach to better examine the change of the wealth of more impoverished populations into growth and distribution effects.
Yamada, Takahiro
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Income Distribution In Brazil 1981-1990 Parametric and Non-Parametric Approach

open access: yes, 1999
We examine changes in the shape of the Brazilian income distribution during the “lost decade” of the 1980s, using a recently available comprehensive micro-data set.
Ferreira, Francisco H.G.   +2 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Government Policy and Equality of Income Distribution in the Netherlands (1945-1986)

open access: yes, 1992
Inequality of income distribution in the Netherlands has since 1945 strongly been influenced by government policies. Until the end of the 1970s, governments pursued policies designed to reduce income differentials.
van Wijngaarden, P.
core  

Home - About - Disclaimer - Privacy