Results 101 to 110 of about 4,447,981 (197)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Limited-Rivalry Consumer Goods and Income Distribution – An Exploration
Consequences of market provision of consumer goods that are less than fully rival are explored. The feedbacks introduced by limited rivalry are shown to interact with income distribution in ways absent from standard theory. Specifically, it is shown that
Anderson, Fredrik
core
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The question has been asked as to how changes in economic growth affect income distribution. Blinder and Esaki reframed the question to consider inflation and time trends in addition to aggregate income growth.
Haslag, J. H., Slottje, D.J.
core
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The Effects of the Economic Reforms on China’s Income Distribution In the Past Ten Years
Since late 1970’s, China has adopted the economic policies of ‘making the internal economy alive and opening doors to foreign countries,’ which have brought about the rapid development of the national economy and the significant improvement in people’s ...
Song, Huang
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Evaluating Changes in the Distribution of Income in the United States
Insights gained from previous macroeconomic studies of the size distribution of U.S. incomes are incorporated into a richer model that considers the possibility of random walks and cointegration. The effects of macroeconomic, demographic, structural, and
Bishop, J. A., Formby, J. P., Sakano, R.
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source

