Results 121 to 130 of about 23,134,989 (378)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Diffusion-Equation-Based Electrical Modeling for High-Power Lithium Titanium Oxide Batteries

open access: yesBatteries
Lithium titanium oxide (LTO) batteries offer superior performance compared to graphite-based anodes in terms of rapid charge/discharge capability and chemical stability, making them promising candidates for fast-charging and power-assist vehicle ...
Haoze Chen   +5 more
doaj   +1 more source

Experimental Investigation of Adaptive Fuzzy Global Sliding Mode Control of Single-Phase Shunt Active Power Filters

open access: yesIEEE Access, 2019
In this paper, an indirect adaptive fuzzy global sliding mode control methods (AFGSMC) are proposed for single-phase shunt active power filter as a current controller.
Shixi Hou   +3 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

A Co-Simulation Method Based on Coupled Thermoelectric Model for Electrical and Thermal Behavior of the Lithium-ion Battery

open access: yesIEEE Access, 2019
Nowadays, the lithium-ion battery (LIB) has been widely used as an energy source for electric vehicles or the auxiliary power supply for rail transit. However, the sensitivity of LIB to temperature greatly limits its application condition.
Weinan Huang   +4 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

A novel WDOB‐based strategy endows droop‐controlled grid‐forming converters better dynamic and static performance in DC microgrids

open access: yesIET Power Electronics
The droop control strategy is popularly employed in DC microgrids. However, its virtual resistance will cause voltage deviation and reduce transient response. The DOB‐based method is proven to improve transient response in literature.
Wenqiang Xie   +3 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

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