Results 71 to 80 of about 6,202,104 (299)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Optimal planning of energy storage system in active distribution system based on fuzzy multi-objective bi-level optimization

open access: yesJournal of Modern Power Systems and Clean Energy, 2017
A fuzzy multi-objective bi-level optimization problem is proposed to model the planning of energy storage system (ESS) in active distribution systems (ADS).
Rui LI, Wei WANG, Zhe CHEN, Xuezhi WU
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dynamic Equivalent Modeling of a Grid-Tied Microgrid Based on Characteristic Model and Measurement Data

open access: yesEnergies, 2017
Microgrids can significantly improve the utilization of distributed generation (DG) and the reliability of the power supply. However, in the grid-tied operational mode, the interaction between the microgrid and the distribution network cannot be ignored.
Changchun Cai   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Blood collection in heparin vs. EDTA results in an inflammasome-independent increase in monocyte distribution width at 4 h

open access: hybrid, 2023
Gregory Eisinger   +6 more
openalex   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Optimal Allocation of Hybrid Energy Storage Systems for Smoothing Photovoltaic Power Fluctuations Considering the Active Power Curtailment of Photovoltaic

open access: yesIEEE Access, 2019
Hybrid energy storage systems (HESSs) have become an effective solution for smoothing the active power variations of photovoltaic (PV). In order to reduce the required capacities and costs of the HESS, a coordinated control scheme is developed to ...
Wei Ma   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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