Results 171 to 180 of about 12,070,426 (318)

Government Policy and Equality of Income Distribution in the Netherlands (1945-1986)

, 1992
Inequality of income distribution in the Netherlands has since 1945 strongly been influenced by government policies. Until the end of the 1970s, governments pursued policies designed to reduce income differentials.
van Wijngaarden, P.
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Genomic distribution characteristics and interspecific differences of microsatellite landscapes in Felidae. [PDF]

BMC Genomics
Dou H, Xi H, Li Y, Yang H, Zhang H, Wang F.   +5 more
europepmc   +1 more source

Limited-Rivalry Consumer Goods and Income Distribution – An Exploration

, 2001
Consequences of market provision of consumer goods that are less than fully rival are explored. The feedbacks introduced by limited rivalry are shown to interact with income distribution in ways absent from standard theory. Specifically, it is shown that
Anderson, Fredrik
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Spatiotemporal distribution characteristics and disease burden of human brucellosis in Inner Mongolia Autonomous Region, 2014-2023. [PDF]

Front Public Health
Zhang Q, He J, Zhu Z, Lan B, Shi H, Zhang Z, Ta N, Chen Q, Xu Y, Zhang W.   +9 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Metastatic organ distribution characteristics and prognosis in patients with non-small cell lung cancer. [PDF]

Front Med (Lausanne)
Zhu J, Pan W, Wang Y.
europepmc   +1 more source

Cyclical Fluctuations, Macroeconomic Policy, and the Size Distribution of Income: Some Preliminary Evidence

, 1995
The question has been asked as to how changes in economic growth affect income distribution. Blinder and Esaki reframed the question to consider inflation and time trends in addition to aggregate income growth.
Haslag, J. H., Slottje, D.J.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source