Results 171 to 180 of about 3,055,792 (311)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Reliability of pair distribution function analysis in <i>in situ</i> experiments. [PDF]

open access: yesJ Appl Crystallogr
Stubkjær RB   +5 more
europepmc   +1 more source

Derivatives of the Incomplete Beta Function

open access: yes
The incomplete beta function is defined as where Beta(p, q) is the beta function. Dutka (1981) gave a history of the development and numerical evaluation of this function. In this article, an algorithm for computing first and second derivatives of Ix,p,q
James F. Robinson-Cox, Robert J. Boik
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Evaluating Kolmogorov's Distribution

open access: yes
Kolmogorov's goodness-of-fit measure, D_n , for a sample CDF has consistently been set aside for methods such as the D^+_n or D^-_n of Smirnov, primarily, it seems, because of the difficulty of computing the distribution of D_n .
George Marsaglia   +2 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Hydroxycinnamic acid amides in rice: biosynthesis, distribution, function, and implication for crop development. [PDF]

open access: yesFront Plant Sci
Xue R   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy