Results 31 to 40 of about 140,324 (269)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Dynamic items delivery network: prediction and clustering

open access: yesHeliyon, 2021
Items delivery companies generally use a model to minimize delivery costs. From a mathematical perspective, the model is an objective function that involves constraints.
Mokhammad R. Yudhanegara   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Teachers' Competence and Readiness in Eco-Green Mathematics and Environmental Sustainability Literacy: An Empirical Study in Digital-AI-Based Learning [PDF]

open access: yesBIO Web of Conferences
This study investigates mathematics teachers' competencies and readiness in integrating Eco-Green Mathematics, sustainability literacy, and digital-AI-based learning.
Sunismi Sunismi   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Relationships between Teacher Quality and Sixth Grade Students’ Mathematics Competencies in Kenya and Zimbabwe

open access: yesAfrican Journal of Teacher Education, 2018
Students should begin to engage in problem-solving and higher order thinking skills in mathematics in the early years of school in preparation for 21st-century technology and problem-solving competencies.
Rachel Angela Ayieko   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The lifecontingencies Package: Performing Financial and Actuarial Mathematics Calculations in R

open access: yesJournal of Statistical Software, 2013
It is possible to model life contingency insurances with the lifecontingencies R package, which is capable of performing financial and actuarial mathematics calculations.
Giorgio Alfredo Spedicato
doaj   +1 more source

Reflecting on dilemmas in digital resource design as a response to COVID-19 for learners in under-resourced contexts

open access: yesPythagoras, 2021
The coronavirus disease 2019 (COVID-19) pandemic and the resulting school closures in South Africa necessitated a major shift in how to support learners’ ongoing mathematics learning.
Pamela Vale, Mellony H. Graven
doaj   +1 more source

Mathematical model for the distribution of DNA replication origins

open access: yesPhysical Review E, 2023
DNA replication in yeast and in many other organisms starts from well-defined locations on the DNA known as replication origins. The spatial distribution of these origins in the genome is particularly important in ensuring that replication is completed quickly. Cells are more vulnerable to DNA damage and other forms of stress while they are replicating
Alessandro de Moura, Jens Karschau
openaire   +3 more sources

Home - About - Disclaimer - Privacy