Results 171 to 180 of about 166,083,503 (302)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Neural correlates of affective self-positivity bias in first and second languages. [PDF]

Front Psychol
Kong C, Liu H, Schwieter JW, Muñoz F.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Ecological and Economic Distribution as Elements of the Evolution of Modern Societies

, 1997
The evolution of modern market economies can be evaluated in terms of distribution- as distinguished from efficiency. But distribution is not only given in economic terms.
Beckenbach, F.
core  

Orthographic codes in visual word recognition: Task-dependent effects with insertions and deletions of repeated and unique letters. [PDF]

Mem Cognit
Adelman JS, Trifonova IV.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

miniMORPH: A Morphometry Pipeline for Low-Field MRI in Infants. [PDF]

Hum Brain Mapp
Casella C, Leknes A, Bourke NJ, Zahra A, Cromb D, Barnes D, Segura AM, Silvester F, Kyriakopoulou V, Scheiene DE, Williams SR, Bradford LE, Murungi J, Williams SCR, Deoni SCL, Nankabirwa V, Donald KA, Bruchhage MMK, O'Muircheartaigh J.   +18 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Income distribution and macroeconomics in Colombia

, 2007
This paper studies the relation between macroeconomic variables and the distribution of income in Colombia. We relate the dynamics of aggregate economic variables with the cross-section of disaggregate income to determine the transmission and propagation
Birchenall, Javier A.
core  

Context-dependent Modulation of Visual Recognition by Conscious and Unconscious Priming. [PDF]

Basic Clin Neurosci
Kashani SN, Khosrowabadi R, Dehaqani MA.
europepmc   +1 more source