Results 131 to 140 of about 1,853,872 (317)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Pattern classification via unsupervised learners [PDF]
We consider classification problems in a variant of the Probably Approximately Correct (PAC)-learning framework, in which an unsupervised learner creates a discriminant function over each class and observations are labeled by the learner returning the ...
Palmer, Nicholas James
core
Dynamic pattern denoising method using multi-basin system with kernels
, 2018 In this paper, we propose a novel pattern denoising method that utilizes the topological property of a support that describes the distribution of normal patterns to denoise noisy patterns.
Jung, KH, Lee, J, Kim, N
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Distribution pattern of intraspecific variation and interspecific divergence.
, 2013 Distribution pattern of intraspecific variation and interspecific divergence.
Aibing Zhang (500760) +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Estimating the Distribution of Dietary Consumption Patterns
Statistical Science, 2014 In the United States the preferred method of obtaining dietary intake data is the 24-hour dietary recall, yet the measure of most interest is usual or long-term average daily intake, which is impossible to measure. Thus, usual dietary intake is assessed with considerable measurement error. We were interested in estimating the population distribution of
openaire +5 more sources
The distribution ratio of color pattern of Hemerocallis.
, 2019 The distribution ratio of color pattern of Hemerocallis.
Feifei Gong (6807512) +7 more
core +1 more source