Results 211 to 220 of about 23,558,939 (264)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Integrating Distributed Algorithms into Distributed Systems [PDF]

open access: possibleFundamenta Informaticae, 1999
A distributed algorithm is often used as a part of a larger distributed system. Usually, the properties of an algorithm are proven for the algorithm in isolation. Then, it is not obvious how the algorithm behaves when integrated into a larger system. In this paper, we present a simple technique which allows to derive properties of an algorithm which is
Ekkart Kindler, Sibylle Peuker
openaire   +2 more sources
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Dissipative distributed systems

Proceedings of the 39th IEEE Conference on Decision and Control (Cat. No.00CH37187), 2002
Deals with systems described by constant coefficient linear partial differential equations. We define dissipativity with respect to a quadratic differential form, i.e., a quadratic functional in the system variables and their partial derivatives. The main result states the equivalence of dissipativity and the existence of a storage function or of a ...
Harish K. Pillai, Jan C. Willems
openaire   +2 more sources

Distributed Systems

Computer, 1985
Growth of distributed systems has attained unstoppable momentum. If we better understood how to think about, analyze, and design distributed systems, we could direct their implementation with more confidence.
openaire   +3 more sources

On a System of Discrete Distributions

Biometrika, 1967
Using the difference equation analogous to Pearson's differential equation, a system of discreate distributions is developed. This is found to contain many of the distributions in common usage. The choice of distribution usually depends on only the first three moments. Some examples are given.
openaire   +3 more sources

Testing a distributed system

Communications of the ACM, 2015
Testing a distributed system can be trying even under the best of circumstances.
openaire   +2 more sources

Load distributing for locally distributed systems

Computer, 1992
The problem of judiciously and transparently redistributing the load of the system among its nodes so that overall performance is maximized is discussed. Several key issues in load distributing for general-purpose systems, including the motivations and design trade-offs for load-distributing algorithms, are reviewed.
Niranjan G. Shivaratri   +2 more
openaire   +2 more sources

Monitoring distributed systems with distributed algorithms

Proceedings of the 41st IEEE Conference on Decision and Control, 2002., 2003
Proposes a framework to process large distributed systems by parts, through distributed algorithms. We consider distributed (discrete event) systems as the combination of elementary components. Each component defines dynamics on several state variables, and the composition is simply defined by sharing variables.
Eric Fabre, Vincent Pigourier
openaire   +1 more source

Distributing Distributed Revision Control Systems

2016 IEEE 41st Conference on Local Computer Networks (LCN), 2016
Current revision control systems are commonly used in a distributed fashion but rely on centralized stores and low-latency communication. In this work we evaluate how they would fare in fully distributed high latency networks such as delay tolerant networks (DTNs).
Philipp Hagemeister, Martin Mauve
openaire   +1 more source

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