Results 71 to 80 of about 3,308,530 (269)

The effects of priming intermittent theta-burst stimulation on phase-amplitude coupling and its directionality in Alzheimer’s disease rats

Brain-Apparatus Communication
Aim Intermittent theta burst stimulation (iTBS) shows promise in alleviating cognitive dysfunction in neurodegenerative diseases. Pre-treatment with iTBS could potentially modulate the threshold of synaptic plasticity, which may enhanc the facilitative ...
Miaomiao Guo, Biao Zhang, Yingxue Zhang, Haodi Zhai, Tian Wang, Shanshan Li, Mengfan Li, Guizhi Xu, Pan Wang, Yong Ji   +9 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A Comprehensive Review of Reliability Analysis for Pulsed Power Supplies

Energies
Achieving high reliability remains the critical challenge for pulsed power supplies (PPS), whose core components are susceptible to severe degradation and catastrophic failure due to long-term operation under electrical, thermal and magnetic stresses ...
Xiaozhen Zhao, Haolin Tong, Haodong Wu, Ahmed Abu-Siada, Kui Li, Chenguo Yao   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Leveraging the charging flexibility of electric vehicles in sequential electricity markets with frequency regulation limit

International Journal of Electrical Power & Energy Systems
As the intraday market plays an important role in absorbing uncertainty from renewable energy sources, deriving trading decisions that optimizing economic benefits across sequential day-ahead and real-time markets become increasingly complex.
Shuang Gao, Shengyu Huang, Xiaolong Jin, Yuming Zhao, Wenjun Tang   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Interruption strategy of fault current fed by high-capacity generator based on phase selection and current-zero prediction

International Journal of Electrical Power & Energy Systems
The high asymmetrical degree (AD, >100 %) of the fault current fed by high-capacity turbine generator (HTG) results in high arc energy (Earc), hindering reliable interruptions of generator circuit breakers (GCBs). Traditional GCBs with simultaneous three-
Jinghan Fan, Weijie Wen, Bin Li, Haiyan Wang, Zhihao Zhu, Xiang Fei   +5 more
doaj   +1 more source

Fault-Tolerant Control for a Flexible Group Battery Energy Storage System Based on Cascaded Multilevel Converters

Energies, 2018
A flexible group battery energy storage system (FGBESS) based on cascaded multilevel converters is attractive for renewable power generation applications because of its high modularity and high power quality.
Junhong Song, Weige Zhang, Hui Liang, Jiuchun Jiang, Wensong Yu   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimal Clearing Strategy for Day-Ahead Energy Markets in Distribution Networks with Multiple Virtual Power Plant Participation

Applied Sciences
Constrained by current market mechanisms, small-scale virtual power plants (SS-VPPs) on the distribution network side struggle to exert their market characteristics.
Pei Wang, Sen Tian, Qian Xiao, Tianxiang Li, Zibo Wang, Ji Qiao, Hong Zhu, Wenlu Ji   +7 more
doaj   +1 more source