Results 81 to 90 of about 3,308,530 (269)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Flexible mesh-shaped distribution network topology with adaptive geographical layered-clustered probabilistic planning

International Journal of Electrical Power & Energy Systems
With the large-scale integration of distributed renewable energy, traditional distribution network topologies lack the flexibility to fully exploit wide-area source-load complementarity and flexible resources, limiting the efficient and secure ...
Shaohan Lu, Hong Liu, Qizhe Li, Peng Zhang, Bo Peng, Bin Xu   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Frequency regulation market participation of distributed energy storage systems

International Journal of Electrical Power & Energy Systems
To promote the effective participation of distributed energy storage systems (DESSs) in the frequency regulation (FR) market, a complete framework for distributed energy storage aggregation service providers (DSAPs) to fully incentivize the DESSs to ...
Tao Xu, Jianhang Sun, He Meng, Rujing Wang, Yu Ji, Ying Zhang, Ping Song, Jiani Xiang   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Empowering PV system modeling and forecasting: a review of public benchmark datasets

Global Energy Interconnection
Driven by the high penetration of renewable energy, the inherent intermittency of photovoltaic (PV) generation poses severe challenges to grid stability. To manage this volatility and ensure reliable grid integration, precise PV system modeling and power
Bochao Zhao, Yaqing Wang, Wenpeng Luan, Hanju Cai   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Flexibility potential of electric vehicle charging: A trip chain analysis under bi-criterion stochastic dynamic user equilibrium

Advances in Applied Energy
The widespread adoption of electric vehicles (EVs) creates opportunities to use EV charging load as a flexible resource to improve grid operation. In urban areas, EV users typically follow trip chains in their daily travel, offering temporal and spatial ...
Shuyi Tang, Yunfei Mu, Hongjie Jia, Xiaolong Jin, Xiaodan Yu   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Quantitative Analysis Method for Full Lifecycle Aging Pathways of Lithium-Ion Battery Systems Based on Equilibrium Potential Reconstruction

Applied Sciences
High-specific-energy lithium-ion batteries face accelerated degradation and safety risks. To ensure stable and safe operation of such batteries in electric vehicles throughout their service life, this study proposes a quantitative aging mechanism ...
Jiaqi Yu, Yanjie Guo, Wenjie Zhang
doaj   +1 more source