Results 171 to 180 of about 41,764,182 (312)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial distribution and associated factors of public healthcare infrastructure in tourism-oriented environments: evidence from Southwest China in the context of residential tourism. [PDF]

Front Public Health
Zhao H, Wei W, Yu S, Wang C.
europepmc   +1 more source

Modelling Income Using the Generalised Lambda Distribution

, 2008
In the present article we propose the generalised lambda distribution as a model for income data. The quantile measures of location, dispersion, skewness, and kurtosis of the distribution are matched against the corresponding measures derived from the ...
Nair, K.R. Muraleedharan, Nair, N. Unnikrishnan, Haridas, Haritha N.   +2 more
core  

Analysis of Distributed Systems

International Journal of Computer Applications
Md Shihab Uddin, Ehteshamul Haque, Anwarul Azim Bhuiyan, Tasmita Tanjim Tanha, Ehsan Bazgir   +4 more
openaire   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A protection strategy for distribution networks using IoT technology and support vector machine. [PDF]

Sci Rep
Shalby EM, Abdelaziz AY, Ahmed ES, Rashad BA.   +3 more
europepmc   +1 more source

Reliability Evaluation of Distribution Systems

Reliability of the electric power supply is essential in modern society. The electric power system with its generation, as well as its transmission and distribution networks, is one of the most complex technical systems that humanity has created ...
Zemīte, Laila, Gerhards, Jānis
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Water quality analysis of a nontraditional distribution system in Trujillo Peru

Annals of Global Health, 2016
J.A. Green, C. Leiser, M. Stewart, K. Zappas, A. Schwei, L.S. Benson   +5 more
doaj   +1 more source

A Morality Based Target Audience Analysis and Quantum Open System Interaction Model for Propaganda. [PDF]

Entropy (Basel)
Canan M.
europepmc   +1 more source