Results 231 to 240 of about 41,764,182 (312)

Inter-domain distance analysis reveals conformational changes in the Keap1-Nrf2 stress sensor system. [PDF]

Redox Biol
Saito R, Kawabata T, Yamashita S, Oki K, Fujii T, Kawauchi H, Doi Y, Irie M, Torizawa T, Kinoshita K, Yamamoto M, Koshiba S.   +11 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A probabilistic multi objective decision framework for reactive power planning in der integrated microgrids enhancing sustainability and resilience in the egyptian grid. [PDF]

Sci Rep
Elazab R, Sakr EK, Abo-Adma M, Mohammed A.   +3 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Molecular Dynamics Study of Supramolecular Complexes to the Carbohydrate-Cation System. [PDF]

F1000Res
Kafi DK, Mohi AT.
europepmc   +1 more source

Ex-ante assessment of novel technologies for bio-based chemicals production [PDF]

, 2018
Moncada Botero, J., Energy System Analysis   +1 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Spatial heterogeneity in area-level environmental context of hospital-based congenital structural anomaly burden in Southwest China: a retrospective study from a provincial pediatric referral center. [PDF]

World J Pediatr
Zhanghuang CH, Ma YY, Zheng CL, Hu X, Zhang MX, Gao YP, Chen JR, Yang SW, Zhang H, Dai RT, Zhang XC, Shen J, Yan B, Wu J.   +13 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Adaptive teaching assistance model combining generative AI and big data analytics. [PDF]

Front Psychol
Zhu Z, Luo C, Li L.
europepmc   +1 more source