Results 251 to 260 of about 41,764,182 (312)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Scoring Mating System of a Natural Population of <i>Neolamarckia cadamba</i> with Genome Resequencing Data. [PDF]

Biology (Basel)
Wu C, Gao ZY, Xie H, Ouyang KX, Que QM, Hu XS.   +5 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Thermal Stress and Temperature Analysis of Integrated Protection-Thermal Control Multilayer Films Under Laser Irradiation in Alternating High and Low Temperatures. [PDF]

Materials (Basel)
Zhou C, Zhu R, Cao S, Yang J, Gui B.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Comparative finite element analysis of a novel distal tibiofibular locking plate versus conventional fixation methods for Tillaux-Chaput fractures. [PDF]

Front Bioeng Biotechnol
Hu X, Liao F, Que W, Huang H, Li H, Liu H, Lan W, Chen R.   +7 more
europepmc   +1 more source

Morpho-electrochemical behavior of particulate Zn electrodes revealed by X-ray and neutron tomography. [PDF]

Sci Rep
Bozzini B, Casamichiela F, Emanuele E, Favalli A, Ferretti R, Looman M, Pola A, Sodini N, Strada J, Vaccaro S.   +9 more
europepmc   +1 more source

One Health in hospital settings: the role of water as an invisible reservoir of opportunistic pathogens. [PDF]

Braz J Microbiol
Ferreira EB, da Silva JL, Mattos MSF, Martinez HV, Pilau EJ, Tognim MCB, Gimenes F, Machinski Junior M, de Abreu Filho BA.   +8 more
europepmc   +1 more source

Optimal integration of electric vehicle charging stations and distributed generator in microgrids using bio-inspired optimization techniques. [PDF]

Sci Rep
Omar AI, Elbaz MM, Ali MN, Hussien SA, Keshta HE.   +4 more
europepmc   +1 more source

Characteristics of pediatric drug-related investigator-initiated trials in Chinese children's hospitals: a comparative analysis based on ChiCTR and ClinicalTrials.gov registration data. [PDF]

Front Pharmacol
Yang Y, Zhang D, Yang S, Yao Z.
europepmc   +1 more source