Results 61 to 70 of about 9,044 (253)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Consensus Decision Modeling with Distributionally Robust Chance Constraint in Uncertain Environments

Journal of Mathematics, 2023
Group decision-making (GDM) in an ambiguous environment has consistently become a research focus in the decision science field during the past decade. Existing minimum cost consensus models either control the total budget in a deterministic context or ...
Dai Zexing, Fang Zhiming, Cheng Panhong, Qin Jiayi   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Distributionally Robust Game-Theoretic Optimization Algorithm for Microgrid Based on Green Certificate–Carbon Trading Mechanism

Energies
Aiming at multi-agent interest demands and environmental benefits, a distributionally robust game-theoretic optimization algorithm based on a green certificate–carbon trading mechanism is proposed for uncertain microgrids. At first, correlated wind–solar
Chen Wei, Pengyuan Zheng, Jiabin Xue, Guanglin Song, Dong Wang   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Distributionally Robust Bootstrap Optimization

, 2021
Control architectures and autonomy stacks for complex engineering systems are often divided into layers to decompose a complex problem and solution into distinct, manageable sub-problems. To simplify designs, uncertainties are often ignored across layers, an approach with deep roots in classical notions of separation and certainty equivalence.
Summers, Tyler, Kamgarpour, Maryam
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cooperative Operation Optimization for Multi-region Hydrogen-Integrated Integrated Energy System Based on Hybrid Wasserstein Two-Stage Distributionally Robust

Zhongguo dianli
An integrated energy system (IES) coupled with hydrogen energy is significantly influenced by source-load uncertainties when operating alone. Traditional robust optimization techniques are overly conservative, which impedes the economic performance.
Xiaoqiang DING, Zhi YUAN, Ji LI
doaj   +1 more source

Distributionally Robust Observable Strategic Queues

Stochastic Systems
This paper presents an extension of Naor’s analysis on the join-or-balk problem in observable M/M/1 queues. Although all other Markovian assumptions still hold, we explore this problem assuming uncertain arrival rates under the distributionally robust settings. We first study the problem with the classical moment ambiguity set, where the support, mean,
Yijie Wang, Madhushini Narayana Prasad, Grani A. Hanasusanto, John J. Hasenbein   +3 more
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source