Results 81 to 90 of about 9,044 (253)
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Distributionally Robust Recourse Action
, 2023 A recourse action aims to explain a particular algorithmic decision by showing one specific way in which the instance could be modified to receive an alternate outcome. Existing recourse generation methods often assume that the machine learning model does not change over time.
Nguyen, Duy, Bui, Ngoc, Nguyen, Viet Anh
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Zhejiang dianliThe volatility of renewable energy generation accelerates the aging of water distributionally robust optimization within Power-to-Gas （P2G） stations. Existing optimization models fail to effectively account for the impact of wide power fluctuations on ...
SUN Yifan, WANG Lin, JIN Xiao
doaj +1 more source
Distributionally Robust Adaptive Beamforming
IEEE Transactions on Signal ProcessingAs a fundamental technique in array signal processing, beamforming plays a crucial role in amplifying signals of interest (SoI) while mitigating interference plus noise (IPN). When uncertainties exist in the signal model or the data size of snapshots is limited, the performance of beamformers significantly degrades.
Shixiong Wang, Wei Dai, Geoffrey Ye Li
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
A hierarchical deep learning and distributionally robust framework for urban multi-energy systems
Results in EngineeringThis paper presents a hierarchical optimization framework for distributed energy management in urban multi-energy systems that integrates deep learning-based forecasting with distributionally robust optimization.
Mohammad Heydari +2 more
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
, 2019 Two-stage stochastic optimization is a framework for modeling uncertainty, where we have a probability distribution over possible realizations of the data, called scenarios, and decisions are taken in two stages: we make first-stage decisions knowing ...
Linhares, Andre, Swamy, Chaitanya
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source