Results 121 to 130 of about 6,626 (272)
Distributionally Robust Optimization and Robust Statistics
We review distributionally robust optimization (DRO), a principled approach for constructing statistical estimators that hedge against the impact of deviations in the expected loss between the training and deployment environments. Many well-known estimators in statistics and machine learning (e.g.
Blanchet, Jose +3 more
openaire +2 more sources
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
In this paper, we propose a data-driven distributionally robust optimization (DRO) framework that ensures the economical and robust operation of solar photovoltaic (PV)-integrated battery charging swapping stations (BCSSs) for electric vehicles (EVs ...
Haram Kim, Sangyoon Lee, Dae-Hyun Choi
doaj +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Robust Expansion Planning of Electric Vehicle Charging System and Distribution Networks
Large integration of electric vehicles (EVs) brings uncertainties and challenges for distribution networks. Reliability and allocation of charging systems (charging stations and piles) need strong support from the distribution network, whose expansion ...
Yue Xiang +7 more
doaj +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Deciding the locations of shelters and how to assign evacuees to these locations is crucial for effective disaster management. However, the inherent uncertainty in evacuation demand makes it challenging to make optimal decisions.
Kai Tang, Toshihiro Osaragi
doaj +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
On the one hand, carbon tax is an environmental policy aimed at reducing carbon dioxide emissions, but it is difficult to implement in areas relying on coal combustion and other carbon intensive areas.
XU Min, SONG Wenqin, WANG Zhuxiu
doaj +1 more source

