Results 111 to 120 of about 1,702,253 (317)

Universal Approximation and the Topological Neural Network

open access: yesIEEE Access
A topological neural network (TNN), which takes input data from a Tychonoff topological space instead of the usual finite dimensional space, is introduced.
Michael A. Kouritzin, Daniel Richard
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Heavy-tailed distributions in VaR calculations [PDF]

open access: yes
The essence of the Value-at-Risk (VaR) and Expected Shortfall (ES) computations is estimation of low quantiles in the portfolio return distributions.
Rafal Weron, Adam Misiorek
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Comparisons of Heterogeneous Distributions and Dominance Criteria [PDF]

open access: yes
We are interested in the comparisons of standard-of-living across societies when observations of both income and household structure are available. We generalise the approach of Atkinson and Bourguignon (1987) to the case where the marginal distributions
Patrick MOYES (GREThA et IDEP Marseille)
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Model Comparison of Coordinate-Free Multivariate Skewed Distributions with an Application to Stochastic Frontiers [PDF]

open access: yes
We consider classes of multivariate distributions which can model skewness and are closed under orthogonal transformations. We review two classes of such distributions proposed in the literature and focus our attention on a particular, yet quite flexible,
Jose T.A.S. Ferreira, Mark F.J. Steel
core  

Sequences of elliptical distributions and mixtures of normal distributions

open access: yes, 2006
Two conditions are shown under which elliptical distributions are scale mixtures of normal distributions with respect to probability distributions. The issue of finding the mixing distribution function is also considered.
Marín Díazaraque, Juan Miguel   +5 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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