Results 81 to 90 of about 2,000,911 (262)

Functionals with values in the non‐Archimedean field of Laurent series and their applications to the equations of elasticity theory

open access: yesMathematical Modelling and Analysis, 2003
Functionals with values in Non‐Archimedean field of Laurent series applied to the definition of generalized solution (in the form of shock wave) of the Hopf equation and equations of elasticity theory.
M. Radyna
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Topology optimization for elastic base under rectangular plate subjected to moving load

open access: yesArchives of Control Sciences, 2015
Distribution optimization of elastic material under elastic isotropic rectangular thin plate subjected to concentrated moving load is investigated in the present paper. The aim of optimization is to damp its vibrations in finite (fixed) time.
Jilavyan Samvel H.   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Firm Size Distributions : An overview of steady-state distributions resulting from firm dynamics models [PDF]

open access: yes
Empirical firm size distributions are the cumulated result of underlying firm dynamics involving entry of new firms and growth, decline, and exits of incumbent firms. In this improved version of the research report "Firm size distributions" (H200306), we
Gerrit de Wit
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Computation of microdosimetric distributions for small sites [PDF]

open access: yes, 1977
Object of this study is the computation of microdosimetric functions for sites which are too small to permit experimental determination of the distributions by Rossi-counters.
Kellerer, Albrecht M., Chmelevsky, D.
core   +1 more source

HidroEsta, software for hydrological calculations

open access: yesTecnología en Marcha, 2016
This investigation, “HidroEsta, software for Hydrological Calculations” is oriented towards the creation of a computing tool using Visual Basic intended to facilitate and simplify difficult calculations that must be carried out in hydrological studies ...
Máximo Villón-Béjar
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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