Results 71 to 80 of about 2,278 (280)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Congruence lattices of free lattices in non-distributive varieties
, 1998 We prove that for any free lattice F with at least $\aleph_2$ generators in any non-distributive variety of lattices, there exists no sectionally complemented lattice L with congruence lattice isomorphic to the one of F. This solves a question formulated
Friedrich Wehrung +5 more
core +1 more source
Closed ss-semilocal modules and rings
Open MathematicsA module A is designated as closed ss -semilocal module provided for any closed submodule G of A, there exists a submodule H of A such that A = G + H and G ∩ H ≤ Soc s(A) where Soc s(A) = Rad(A) ∩ Soc(A) and a ring S is named as closed ss -semilocal ring
Önal Kır Emine
doaj +1 more source
Modules with Copure Intersection Property
پژوهشهای ریاضی, 2020 Paper pages (271-276) Introduction Throughout this paper, will denote a commutative ring with identity and will denote the ring of integers. Let be an -module. A submodule of is said to be pure if for every ideal of . has the copure sum property
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modules with locally linearly ordered distributive hulls
, 1987 Let R be a commutative ring with identity and M, N are R-modules with M ⊆ N. Then M ⊆ N is said to be distributive if M∩(X + Y)=(M ∩ Y) + (M ∩ Y), for all submodules, X, Y of N.
Erdoǧdu, V.
core +1 more source
Strongly (Comletely) Hollow Submodules I
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 Let R be a commutative ring with unity and let M be an R-module. In this paper we study strongly (completely) hollow submodules and quasi-hollow submodules.
I. M. A. Hadi, Gh. A. Humod
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