Results 71 to 80 of about 736,343 (218)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Journal of Interventional Epidemiology and Public HealthIntroduction: L’approche World Health Organization Package of Essential Nonconmmunicable (WHOPEN)permet la prévention, la détection précoce et la prise en charge de l’hypertension artérielle (HTA) et diabète.
Bassotom Lakougnon +9 more
doaj +1 more source
Benchmarking Particle Filter Algorithms for Efficient Velodyne-Based Vehicle Localization
Sensors, 2019 Keeping a vehicle well-localized within a prebuilt-map is at the core of any autonomous vehicle navigation system. In this work, we show that both standard SIR sampling and rejection-based optimal sampling are suitable for efficient (10 to 20 ms) real ...
Jose Luis Blanco-Claraco +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Frontiers in EducationIntroductionThis paper is a case study of equity-centered continuous improvement that informed school leader professional learning. The work is a collaboration between researchers and district leaders in Columbus City Schools, USA.
Daniella Molle +4 more
doaj +1 more source
STRUCTURE OF SUNDA IN TANGERANG REGENCY AND THE TERRITORY OF USE
Indonesian Language Education and Literature, 2017 Penelitian ini bertujuan untuk menjelaskan bahasa-bahasa yang berada di wilayah Kabupaten Tangerang. Data berupa bahasa yang digunakan di Kabupaten Tangerang. Data berasal dari bahasa lisan.
Agus Sulaeman
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Studia Ekonomiczne i Regionalne, 2018 Subject and purpose of work: The purpose of the study was to identify the marketing system of cocoa (Theobroma cacao L.) traditionally used by producers in the provinces of Utcubamba and Bagua in the Amazonas region in Peru.
Chávez Vicente M. Castañeda +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source