Results 51 to 60 of about 750,589 (262)

The Formation of the Structures of the West Ukrainian People's Republic (ZUNR) in Ternopil Region in 1918

open access: yesVìsnik - Kiïvsʹkij nacìonalʹnij unìversitet ìmenì Tarasa Ševčenka: Ìstorìâ, 2020
The article deals with the peculiar features of the formation, legitimization and development of administrative, judicial and military structures of the West Ukrainian People’s Republic (ZUNR) in the territory of the southern and central parts of the ...
A. Rukkas, S. Humennyi
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

An Evaluation Framework to Support Optimisation of Scenarios for Energy Efficient Retrofitting of Buildings at the District Level

open access: yesApplied Sciences, 2019
Energy-efficient retrofitting of buildings has become essential to achieve the environmental objectives of the European Union’s (EU) strategies towards reducing carbon emissions and energy dependency on fossil fuels.
Miguel Á. García-Fuentes   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

RESULTS OF STUDYING THE FAUNA OF SPIDERS (ARANEI) REPUBLIC OF DAGESTAN

open access: yesЮг России: экология, развитие, 2014
The results of study of the spiders fauna of Daghestan on 2011 were summed up at most in the work. The annotated lost of species was cited according to the world catalogue of Norman Platnik [1].
G. M. Abdurakhmanov, S. V. Alieva
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Molecular characterization, DNA fingerprinting and genetic diversity analysis of Nepalese rice landraces using SSR markers

open access: yesNepal Journal of Biotechnology
Rice (Oryza sativa) is the major crop of Nepal. Genetic diversity studies in rice have been conducted extensively with collections from various parts of the world, including Nepal.
Bal Krishna Joshi   +3 more
doaj   +1 more source

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