Results 111 to 120 of about 796,821 (312)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Comprehensive Benefit Assessment and Incentive Mechanism of Distributed Photovoltaic Energy Storage System

open access: yes发电技术, 2018
The penetration of distributed energy in the distribution network is increasing, which has caused great pressure to the power grid. The combination of energy storage and distributed generation system can reduce unstable electric energy into the network ...
Xinyi DENG, Xin AI
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Performance evaluation of a low temperature district heating system based on simulation, uncertainty and sensitivity analysis [PDF]

open access: yes, 2013
This paper describes the simulation model and the performance evaluation of a low energy district heating distribution network which supplies heat to 75 apartments.
Himpe, Eline   +2 more
core   +1 more source

Assessment of the Thermal Energy Storage in Friedrichshafen District Energy Systems

open access: yesEnergy Procedia, 2017
Abstract The thermal energy storage (TES) of an actual district energy (DE) system is analyzed thermodynamically, using energy and exergy approaches. With a case study, the results for the TES of the DE system are verified with previous studies. The actual case considered is the Friedrichshafen DE system in Germany.
Behnaz Rezaie   +2 more
openaire   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Development of an Agent-Based System for Decentralized Control of District Energy Systems

open access: yes2019 24th International Conference on Methods and Models in Automation and Robotics (MMAR), 2019
This contribution introduces a new system for distributed model predictive control of energy systems. This system uses multiple agents where each agents optimizes a subsystem. A central instance coordinates the individual agents and takes care of feasibility of the combination of the single solutions.
Jakob M. Fritz   +2 more
openaire   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Effect of Particle Agglomeration on Thermal Conductivity of Solar Salt Nanofluids

open access: yes发电技术
ObjectivesNanofluid technology is an important means to improve the thermal conductivity of energy storage materials in solar thermal power plants. However, the nanoparticles in actual molten salt based nanofluid usually aggregate and settle down, which ...
QIU Lixiang   +4 more
doaj   +1 more source

Design and Implementation of Energy Management System for Residential District [PDF]

open access: yes, 2016
近些年来,为了实现对住宅小区内能源的智能化控制,住宅小区能源管理系统已经成为研究的热点问题。国内外的部分大型公司已经提出了它们的相关设计产品,并在部分地方进行试点。然而,在我国小区智能化进程中,由于受到大部分城区能源网络比较老化的限制,全面推广小区智能化遇到了诸如能源网络改造工程大、时间久、成本高等问题。本文是针对我国旧式小区能源网络而提出的一款住宅小区能源管理系统(HEMS),在不需要对现有的能源网络进行大幅度改造的前提下,实现住宅内能源使用的远程管控 ...
陈丽琳
core  

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