Results 41 to 50 of about 796,821 (312)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Simulation models and performance assessment of district heating substations [PDF]

, 2014
Development of new technologies and methodologies regarding district heating substation operational control strategies are increasingly found nowadays.
Himpe, Eline, Janssens, Arnold, Vaillant Rebollar, Julio   +2 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Operational planning and bidding for district heating systems with uncertain renewable energy production [PDF]

, 2018
In countries with an extended use of district heating (DH), the integrated operation of DH and power systems can increase the flexibility of the power system achieving a higher integration of renewable energy sources (RES).
Andersen, Anders N., Blanco, Ignacio, Guericke, Daniela, Madsen, Henrik   +3 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Digital twin‐based online resilience scheduling for microgrids: An approach combining imitative learning and deep reinforcement learning

IET Renewable Power Generation
Strong uncertainty of renewables puts high demands on the fast response of flexibility resources and resilience‐oriented optimal scheduling for microgrids (MGs).
Haonan Sun, Nian Liu, Lu Tan, Peng Du, Bocheng Zhang   +4 more
doaj   +1 more source

Fortissat minewater geothermal district heating project: case study [PDF]

, 2017
This study summarises the findings of a feasibility assessment for a potential minewater geothermal energy system in the vicinity of the James Hutton Institute’s Hartwood Home Farm, North Lanarkshire in Scotland’s Central Belt. This study aimed to assess
Banks, David, Barron, Hugh, Harnmeijer, Jelte, Lu, Hong, Nikolakopoulou, Valia, Schlicke, Alex, Steen, Paul, Townsend, David, Zhengao, Chen   +8 more
core   +1 more source

Smart energy systems and 4th generation district heating [PDF]

Energy, 2016
This editorial gives an introduction to the important relationship between Smart Energy Systems and 4th Generation District Heating and presents a number of selected papers from the 1st International Conference on the topic. All of the papers elaborate on or otherwise contribute to the theoretical scientific understanding on how we can design and ...
Lund, Henrik, Duic, Neven, Østergaard, Poul Alberg, Mathiesen, Brian Vad; id_orcid 0000-0003-3917-1184   +3 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Modeling and Dynamic Characteristic Analysis of Combustion Process of Biomass Vibrating Grate Furnace

发电技术
In order to explore the combustion characteristics of the biomass vibrating grate furnace and realize the control and optimization of the unit combustion process, the mechanism model of the grate combustion process was established through the analysis of
JIANG Haiwei, GAO Mingming, LI Jie, YU Haoyang, YUE Guangxi, HUANG Zhong   +5 more
doaj   +1 more source