Results 51 to 60 of about 73,028 (265)

Multi-Microgrid Energy Management Strategy Based on Multi-Agent Deep Reinforcement Learning with Prioritized Experience Replay

open access: yesApplied Sciences, 2023
The multi-microgrid (MMG) system has attracted more and more attention due to its low carbon emissions and flexibility. This paper proposes a multi-agent reinforcement learning algorithm for real-time energy management of an MMG. In this problem, the MMG
Guodong Guo, Yanfeng Gong
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Online Modelling and Calculation for Operating Temperature of Silicon-Based PV Modules Based on BP-ANN

open access: yesInternational Journal of Photoenergy, 2017
The operating temperature of silicon-based solar modules has a significant effect on the electrical performance and power generation efficiency of photovoltaic (PV) modules. It is an important parameter for PV system modeling, performance evaluation, and
Honglu Zhu   +6 more
doaj   +1 more source

Planning of Electric Vehicle Charging Infrastructure for Urban Areas with Tight Land Supply

open access: yesEnergies, 2018
Motivated by the development of electric vehicles (EVs), this paper addresses the planning of EV charging infrastructures (EVCIs). Considering that the optimal locations for EVCIs in most cities with a tight land supply are difficult to obtain, it is ...
Chunlin Guo, Jingjing Yang, Lin Yang
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Optimal Operation Method for Microgrid with Wind/PV/Diesel Generator/Battery and Desalination

open access: yesJournal of Applied Mathematics, 2014
The power supply mode of island microgrid with a variety of complementary energy resources is one of the most effective ways to solve the problem of future island power supply. Based on the characteristics of seawater desalination system and water demand
Qingfeng Tang, Nian Liu, Jianhua Zhang
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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