Results 21 to 30 of about 725,179 (250)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Stand Dynamics and Disturbance History of Champlain Valley Clayplain Forests [PDF]

, 2017
Studies of stand dynamics can explain how species interactions and disturbances drive forest structure and recruitment patterns of tree species. It is difficult to generate an understanding of stand dynamics and successional trends of forests in areas ...
Murray, Helena F
core   +1 more source

Drag-free and attitude control for the GOCE satellite [PDF]

, 2008
The paper concerns Drag-Free and Attitude Control of the European satellite Gravity field and steady-state Ocean Circulation Explorer (GOCE) during the science phase.
Aguirre-Martinez, Bertotti, Canuto, Canuto, Canuto, Donati, Enrico Canuto, Fichter, Luenberger, Picone, Scheeres, Silvestrin, Touboul, Vaillon   +13 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Toward an Improved Conceptual Understanding of North American Tree Species Distributions

, 2017
Species distributions have often been assumed to represent climatic limitations, yet recent evidence has challenged these assumptions and emphasized the potential importance of biotic interactions, dispersal limitation, and disturbance.
Copenhaver-Parry, Paige E
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Interpreting Soft Sediment Deformation and Mass Transport Deposits as Seismites in the Dead Sea Depocenter [PDF]

, 2018
Peer reviewedPublisher ...
Agnon, Al-Zoubi, Alsop, Alsop, Alsop, Alsop, Alsop, Alsop, Ambraseys, Amiran, Avşar, Baas, Babonneau, Bartov, Bartov, Becker, Begin, Begin, Ben-Menahem, Berryman, Brink, Calvo, Carton, Cukur, El-Isa, Enzel, Field, Freund, Garfunkel, Garfunkel, Garfunkel, Garfunkel, Gladkov, Greb, Haase-Schramm, Heifetz, Hsü, Jiang, Kagan, Kagan, Kagan, Katz, Ken-Tor, Kitagawa, Klinger, Li, Liu-Zeng, Lu, Manspeizer, Marco, Marco, Marco, Marco, McHugh, McHugh, McHugh, McHugh, McHugh, McKEE, Migowski, Moernaut, Moernaut, Molina, Monecke, Monecke, Moretti, Moretti, Moretti, Neev, Nehorai, Neugebauer, Owen, Papatheodorou, Pedersen, Piper, Polonia, Praet, Prasad, Sakaguchi, Scharer, Schnellmann, Schnellmann, Schramm, Seilacher, Shapira, Shilts, Sims, Sims, Sirkes, Smith, Sneh, Stein, Stein, Stein, Stiller, Strasser, Strasser, Strasser, Torfstein, Torfstein, Van Daele, Van Daele, Van Loon, Waldmann, Wetzler, Wilhelm   +105 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Financial Disturbances and Depressions: The View from Economic History [PDF]

SSRN Electronic Journal, 1999
Events of the past quarter century have renewed the interest of economic historians in major financial disturbances. The study of financial crises was common before World War II, but for the next quarter century little fresh work was done in the area. The chief exception was J. K. Galbraith's The Great Crash. 1929 (1954). Then came M. Friedman and A. J.
openaire   +3 more sources