Results 61 to 70 of about 1,796,874 (292)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Robust performance of nonlinear systems has attracted phenomenal worldwide attention. It is well known that deviating argument and stochastic disturbance may derail the evolution properties of nonlinear systems.
Jin-E Zhang
doaj +1 more source
Aims The relationship between biodiversity and ecosystem functioning is among the most active areas of ecological research. Furthermore, enhancing the diversity of degraded ecosystems is a major goal in applied restoration ecology.
Klaus, Valentin H. +5 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Disturbances, such as wildfires, are one of the main drivers of biodiversity dynamics, and their frequency and intensity are expected to increase due to global change.
Quintana, Xavier D. +21 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The radiated electromagnetic disturbance was evaluated by measuring the electric field intensity in a bandwidth of 10 kHz-2.75 GHz near the valve hall, direct-current (DC) area, reactor room, and transformers in a ±320-kV modular multilevel ...
Jian Zhang +4 more
doaj +1 more source
Measurement of micro synthetic jet actuation using intensity of disturbance [PDF]
Synthetic jet actuator (SJA), as a zero-net-mass but non-zero momentum device, has shown great potential in controlling laminar separation caused by adverse pressure gradient in a boundary layer flow.
Hong, G., Walker, P., Walker, P, Hong, G
core
Appendix C. Mean number of species per life form under different intensity of disturbance.
Mean number of species per life form under different intensity of ...
Shekhar R. Biswas (2918768) +1 more
core +1 more source

