Results 181 to 190 of about 24,702 (304)

Geomag Mimetic Dynamically Reconfigurable POSS Framework Enables Antifatigue Solid Electrolyte Interphases for Lithium Metal Anodes

open access: yesAdvanced Science, EarlyView.
A Geomag‐inspired dynamically reconfigurable POSS framework is constructed to form an antifatigue solid electrolyte interphase (SEI) for lithium metal anodes. The rigid POSS nanocages and reversible hydrogen‐bonded junctions enable adaptive stress dissipation and stable Li+ transport during repeated plating/stripping, thereby suppressing dendrite ...
Tianyi Wang   +13 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

<i>Plasmodium falciparum</i> Chloroquine Resistance Transporter (PfCRT) Is a Redox-Dependent Drug Transporter. [PDF]

open access: yesBiochemistry
Chernitsky-Hamd D   +6 more
europepmc   +1 more source

Tumor Microenvironment‐Responsive Nanoreactor Induces Disulfidptosis in Pancreatic Cancer via Metabolic Interference and Redox Catalysis

open access: yesAdvanced Science, EarlyView.
Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu   +10 more
wiley   +1 more source

Inhibition of Low-Density Lipoprotein Oxidation by Cysteamine, Cystamine, Cysteine and Cystine at Lysosomal pH and pH 7.4. [PDF]

open access: yesAntioxidants (Basel)
Parkes EJ   +8 more
europepmc   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

open access: yesAdvanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak   +6 more
wiley   +1 more source

Breaking the Trade‐Off of Mechanical Robustness and Energy Storage Capacity in Phase Change Materials Through a Molecular Design Strategy of Hard‐Segment‐Anchored/Side‐Chain‐Storage

open access: yesAdvanced Science, EarlyView.
To decouple mechanical robustness and energy storage capacity in phase change materials (PCMs), a series of polyurethane‐based PCMs bearing crystallizable alkyl side chains are synthesized via a hard‐segment‐anchored/side‐chain‐storage molecular design.
Huizhou Luo   +6 more
wiley   +1 more source

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