Results 1 to 10 of about 677,026 (312)

Dysregulated Redox Signaling and Its Impact on Inflammatory Pathways, Mitochondrial Dysfunction, Autophagy and Cardiovascular Diseases

Antioxidants
Dysregulated redox signaling, mitochondrial dysfunction and impaired autophagy form an interconnected network that drives inflammatory and immune responses in cardiovascular disease.
Mehnaz Pervin, Judy B. de Haan
doaj   +1 more source

Pro- and Anti-oxidant Properties of Redox-Active Catechol-Chitosan Films

Frontiers in Chemistry, 2019
Catechols are abundant in nature and are believed to perform diverse biological functions that include photoprotection (e.g., melanins), molecular signaling (e.g., catecholamine neurotransmitters), and mechanical adhesion (e.g., mussel glue).
Eunkyoung Kim, Mijeong Kang, Huan Liu, Chunhua Cao, Changsheng Liu, William E. Bentley, Xue Qu, Gregory F. Payne   +7 more
doaj   +1 more source

Amyloid formation and depolymerization of tumor suppressor p16INK4a are regulated by a thiol-dependent redox mechanism

Nature Communications
The conversion of a soluble protein into polymeric amyloid structures is a process that is poorly understood. Here, we describe a fully redox-regulated amyloid system in which cysteine oxidation of the tumor suppressor protein p16INK4a leads to rapid ...
Sarah G. Heath, Shelby G. Gray, Emilie M. Hamzah, Karina M. O’Connor, Stephanie M. Bozonet, Alex D. Botha, Pierre de Cordovez, Nicholas J. Magon, Jennifer D. Naughton, Dylan L. W. Goldsmith, Abigail J. Schwartfeger, Margaret Sunde, Alexander K. Buell, Vanessa K. Morris, Christoph Göbl   +14 more
doaj   +1 more source

Multímetro como sistema de medición alternativo en las valoraciones potenciométricas

Tecnología en Marcha, 2015
En el presente trabajo, experimentalmente se demuestra que las valoraciones potenciométricas usuales en química analítica (acido-base, redox, complejométricas y de halogenuros) pueden llevarse a cabo utilizando como sistema indicador de punto de ...
José de Jesús Pérez-Saavedra, Sonia Rincón-Arce, Miguel Ángel Cisneros-Valladares   +2 more
doaj   +1 more source

The HOMO-LUMO Gap as Discriminator of Biotic from Abiotic Chemistries

Life
Low-molecular-mass organic chemicals are widely discussed as potential indicators of life in extraterrestrial habitats. However, demarcation lines between biotic chemicals and abiotic chemicals have been difficult to define.
Roman Abrosimov, Bernd Moosmann
doaj   +1 more source

Spermatozoa Proteins Involved in ROS Generation and Antioxidant Defense Are Differentially Acetylated in Idiopathic Infertility

Antioxidants
Idiopathic male infertility (IMI), which accounts for nearly 50% of male infertility cases, remains a major clinical challenge due to the inability of standard semen analysis to reveal underlying molecular defects.
Lisa Goutami, Anwesha Pradhan, Ajaya Kumar Moharana, Soumya Ranjan Jena, Manesh Kumar Panner Selvam, Suresh C. Sikka, Luna Samanta   +6 more
doaj   +1 more source

Cysteine Is the Only Universally Affected and Disfavored Proteomic Amino Acid under Oxidative Conditions in Animals

Antioxidants
Oxidative modifications of amino acid side chains in proteins are a hallmark of oxidative stress, and they are usually regarded as structural damage. However, amino acid oxidation may also have a protective effect and may serve regulatory or structural ...
Mario Schindeldecker, Bernd Moosmann
doaj   +1 more source

Volatiles and Redox Along the East African Rift

Geochemistry, Geophysics, Geosystems
The upper mantle under the Afar Depression in the East African Rift displays some of the slowest seismic wave speeds observed globally. Despite the extreme nature of the geophysical anomaly, lavas that erupted along the East African Rift record modest ...
Maryjo Brounce, Sara Scoggins, Tobias P. Fischer, Heather Ford, Joseph Byrnes   +4 more
doaj   +1 more source

Mechanism-Informed Pharmacotherapy Optimization and Deprescribing: A Redox-Mitochondrial Framework. [PDF]

Pharmacol Res Perspect
Martinc B.
europepmc   +1 more source

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise-Induced Redox Responses in Human Skeletal Muscle. [PDF]

Aging Cell
Ruple BA, Carlini NA, Kofoed JS, Rostamkhani H, Hanson BE, Craig JC, Osburn SC, Manuel AM, Stewart PA, Wanagat J, Broxterman RM, Trinity JD.   +11 more
europepmc   +1 more source