Results 31 to 40 of about 394,071 (267)
Journal of BacteriologyCoenzyme M (2-mercaptoethane sulfonate, CoM) is an essential low-molecular-weight thiol in methanogenic archaea (methanogens) that serves as a methyl carrier and as a component of CoM-S-S-CoB heterodisulfide comprising CoM and coenzyme B (7 ...
Alicia M. Salvi +2 more
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2,2′-[(1E,1′E)-1,2-Phenylenebis(azanylylidene)bis(methanylylidene)]bis(4-bromophenol)
IUCrData, 2017 In the title compound, C20H14Br2N2O2, there are two intramolecular O—H...N hydrogen bonds forming S(6) ring motifs. The outer benzene rings are inclined to the central benzene ring by 39.09 (11) and 24.31 (11)°, and to one another by 37.12 (11)°.
Souad Dekar, Sabrina Bendia, Kamel Ouari
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Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli
Nature Communications, 2022 New cryo-EM structures of the formate hydrogenlyase complex from the model bacterium E. coli clarify how electrons and protons move through the complex and are combined to make H2 gas.
Ralf Steinhilper +3 more
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Frontiers in Chemical BiologyIntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez +4 more
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Charge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes
Molecules, 2022 A series of new charge transfer (CT) chromophores of “α-diimine-MII-catecholate” type (where M is 3d-row transition metals—Cu, Ni, Co) were derived from 4,4′-di-tert-butyl-2,2′-bipyridyl and 3,6-di-tert-butyl-o-benzoquinone (3,6-DTBQ) in accordance with ...
Kira I. Pashanova +7 more
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Redox outside the Box: Linking Extracellular Redox Remodeling with Intracellular Redox Metabolism [PDF]
Journal of Biological Chemistry, 2012 Aerobic organisms generate reactive oxygen species as metabolic side products and must achieve a delicate balance between using them for signaling cellular functions and protecting against collateral damage. Small molecule (e.g. glutathione and cysteine)- and protein (e.g.
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Cell Culture Characterization of Prooxidative Chain-Transfer Agents as Novel Cytostatic Drugs
Molecules, 2021 Prooxidative therapy is a well-established concept in infectiology and parasitology, in which prooxidative drugs like artemisinin and metronidazole play a pivotal clinical role.
Victoria Heymans +3 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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Using the heme peroxidase APEX2 to probe intracellular H2O2 flux and diffusion
Nature CommunicationsCurrently available genetically encoded H2O2 probes report on the thiol redox state of the probe, which means that they reflect the balance between probe thiol oxidation and reduction.
Mohammad Eid +4 more
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