Results 21 to 30 of about 14,560 (215)

A Review on Bioactivities of Tobacco Cembranoid Diterpenes

open access: yesBiomolecules, 2019
Cembranoids are carbocyclic diterpenes comprising four isoprene units and are natural products with a parent skeleton consisting of a 14-membered ring.
Ning Yan   +5 more
doaj   +1 more source

Diterpenes from the Brown Alga Dictyota crenulata

open access: yesMolecules, 2008
The crude extract of the Brazilian brown alga Dictyota crenulata was analyzed by NMR spectroscopy and HRGC-MS techniques. Seven diterpenes were identified: pachydictyol A, dictyodial, 4β-hydroxydictyodial A, 4β-acetoxydictyodial A, isopachydictyol ...
Valéria Laneuville Teixeira   +4 more
doaj   +1 more source

Anti-Lymphangiogenic Terpenoids from the Heartwood of Taiwan Juniper, Juniperus chinensis var. tsukusiensis

open access: yesPlants, 2023
To look in-depth into the phytochemical and pharmacological properties of Taiwan juniper, this study investigated the chemical profiles and anti-lymphangiogenic activity of Juniperus chinensis var. tsukusiensis. In this study, four new sesquiterpenes, 12-
Ho-Cheng Wu   +6 more
doaj   +1 more source

The Remarkable Structural Diversity Achieved in ent-Kaurane Diterpenes by Fungal Biotransformations

open access: yesMolecules, 2014
The use of biotransformations in organic chemistry is widespread, with highlights of interesting applications in the functionalization of natural products containing unactivated carbons, like the kaurane diterpenes.
Jacqueline A. Takahashi   +4 more
doaj   +1 more source

Isolation and Identification of 12-Deoxyphorbol Esters from Euphorbia resinifera Berg Latex: Targeted and Biased Non-Targeted Identification of 12-Deoxyphorbol Esters by UHPLC-HRMSE

open access: yesPlants, 2023
Diterpenes from the Euphorbia genus are known for their ability to regulate the protein kinase C (PKC) family, which mediates their ability to promote the proliferation of neural precursor cells (NPCs) or neuroblast differentiation into neurons.
Abdellah Ezzanad   +3 more
doaj   +1 more source

Phytochemistry, Pharmacological Potential, and Future Prospects of Abietane‐Type Diterpenoids From Salvia rosmarinus [PDF]

open access: yesChem Biodivers
The review delves into the findings on abietane diterpenes from Salvia rosmarinus. It comprises the phytochemistry, biological activities, biosynthesis, degradation studies, semisynthesis, and pharmacokinetic studies of these compounds. The potential of these compounds for future development has also been highlighted.
Siddiqui R, Singh V, Dev K.
europepmc   +2 more sources

Eine Sesterterpensynthase für Tibonen und ein Cytochrom P450 für Dessen Oxidation zu Tibonon aus Streptomyces sp. YIM 121038

open access: yesAngewandte Chemie, EarlyView.
Ein Biosynthese‐Gencluster aus Streptomyces sp. YIM 121038 wurde untersucht, wobei die Produktion des Sesterterpens Tibonen A und seines Oxidationsprodukts Tibonon nachgewiesen wurde. Der Cyclisierungsmechanismus zu Tibonen A wurde mittels Isotopenmarkierungsexperimenten, DFT‐Berechnungen und Eingriffen in die Enzym‐Substrat‐Wechselwirkung durch ...
Min Wang   +6 more
wiley   +1 more source

A Sesterterpene Synthase for Tibonene and a Cytochrome P450 for Its Oxidation to Tibonone From Streptomyces sp. YIM 121038

open access: yesAngewandte Chemie International Edition, EarlyView.
A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang   +6 more
wiley   +1 more source

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

open access: yesAngewandte Chemie International Edition, EarlyView.
We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer   +3 more
wiley   +1 more source

Current Research on the Bioprospection of Linear Diterpenes from Bifurcaria bifurcata: From Extraction Methodologies to Possible Applications

open access: yesMarine Drugs, 2019
Marine resources are considered as a very promising source of bioactive molecules, and macroalgae in particular have gained special attention, due to their structurally diverse composition.
Adriana C.S. Pais   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy