Results 51 to 60 of about 122,430 (320)

Dithiocarbamate as a Valuable Scaffold for the Inhibition of Metallo-β-Lactmases

Biomolecules, 2019
The ‘superbug’ infection caused by metallo-β-lactamases (MβLs) has grown into an emergent health threat. Given the clinical importance of MβLs, a novel scaffold, dithiocarbamate, was constructed.
Ying Ge, Li-Wei Xu, Ya Liu, Le-Yun Sun, Han Gao, Jia-Qi Li, Kewu Yang   +6 more
doaj   +1 more source

The Coordination Chemistry of Imidomethanedithiolate Di-anions: A Structural Comparison with Their Dithiocarbamate Analogs

Inorganics, 2021
A review of the coordination chemistry along with the structural features of heavy element complexes of dithiocarbimate di-anions in the form of [(R)C=NCS2]2− for R = CN, alkyl, and aryl are described.
Peter J. Heard, Yee Seng Tan, Chien Ing Yeo, Edward R. T. Tiekink   +3 more
doaj   +1 more source

New bioconjugated rhenium carbonyls by transmetalation reaction with zinc derivatives [PDF]

, 2012
The transmetallation reaction between zinc dithiocarbamates and rhenium carbonyls has been used as a new strategy to link biomolecules to transition metals.
Alvarez-Larena, Angel, Carrer, Alessia, Lecina i Veciana, Martí, Mazzi, Ulderico, Melendez Alafort, Laura, Suades Ortuño, Joan   +5 more
core   +2 more sources

Synthesis and Antifungal Activity against Fusarium oxysporum of Some Brassinin Analogs Derived from l-tryptophan: A DFT/B3LYP Study on the Reaction Mechanism

Molecules, 2016
An efficient methodology to obtain novel antifungal analogs of brassinin 1 is described. Starting from l-tryptophan 2, N,N′-dialkylthiourea 4, 4-[(1H-indol-3-yl)methylene]-2-sulfanylidene-1,3-thiazolidin-5-one 5 and alkyl (2S)-3-(1H-indol-3-yl)-2 ...
Diego Quiroga, Lili Dahiana Becerra, John Sadat-Bernal, Nathalia Vargas, Ericsson Coy-Barrera   +4 more
doaj   +1 more source

Exploring the topological landscape exhibited by Binary Zinc-triad 1,1-dithiolates [PDF]

, 2018
The crystal chemistry of the zinc-triad binary 1,1-dithiolates, that is, compounds of xanthate [−S2COR], dithiophosphate [−S2P(OR)2], and dithiocarbamate [−S2CNR2] ligands, is reviewed.
Tiekink, Edward R. T. *
core   +1 more source

Bis(N,N-diethyldithiocarbamato-κ2S,S′)(3-hydroxypyridine-κN)zinc and bis[N-(2-hydroxyethyl)-N-methyldithiocarbamato-κ2S,S′](3-hydroxypyridine-κN)zinc: crystal structures and Hirshfeld surface analysis

Acta Crystallographica Section E: Crystallographic Communications, 2016
The common feature of the molecular structures of the title compounds, [Zn(C5H10NS2)2(C5H5NO)], (I), and [Zn(C4H8NOS2)2(C5H5NO)], (II), are NS4 donor sets derived from N-bound hydroxypyridyl ligands and asymmetrically chelating dithiocarbamate ligands ...
Mukesh M. Jotani, Hadi D. Arman, Pavel Poplaukhin, Edward R. T. Tiekink   +3 more
doaj   +1 more source

Cyclometallated Au(III) dithiocarbamate complexes: synthesis, anticancer evaluation and mechanistic studies [PDF]

, 2018
A series of cationic mixed cyclometallated (C^N)Au(III) dithiocarbamate complexes has been synthesized in good yields [HC^N = 2-(p-t-butylphenyl)pyridine]. The crystal structure of [(C^N)AuS2CNEt2]PF6 (3) has been determined.
Bertrand, Benoît, Bochmann, Manfred, Hughes, David L., O'Connell, Maria Anne, Ott, Ingo, Schmidt, Claudia, Searcey, Mark, Waller, Zoe Ann Ella, Williams, Morwen   +8 more
core   +3 more sources

In vitro biological studies of heteroleptic Ag(I) and Cu(I) unsymmetrical N,N′-diarylformamidine dithiocarbamate phosphine complexes; the effect of the metal center

, 2020
A series of five dithiocarbamate and their respective Ag(I) and Cu(I) triphenylphosphine complexes of the general formula [Ag/Cu(PPh3)2L] were synthesized and characterized. The dithiocarbamate ligands were synthesized from formamidines with substituents
S. Oladipo, Chunderika. Mocktar, B. Omondi   +2 more
semanticscholar   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Safety, Tolerability, and Pharmacokinetics of GMDTC for Cadmium Poisoning: A Randomized Phase 1a/1b Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Cadmium exposure causes serious health consequences; however, there is no clinically approved antidote for cadmium poisoning. This Phase 1a/1b trial aimed to investigate safety, tolerability, and pharmacokinetics of Sodium (S)‐2‐(dithiocarboxylato((2S,3R,4R,5R)‐2,3,4,5,6‐pentahydroxyhexyl) amino)‐4‐(methylthio) butanoate (GMDTC), a novel chelating ...
Xuefeng Ren, Wei Hu, Xiaobin Deng, Rong Ma, Fang Pei, Xushen Chen, Xuemei Wang, Jixin Tang, Yan Lai, Shangming Pan, Zhiyong Zhong, Sheng Fu, Huamin Yuan, Juan Yuan, Chuntao Huang, Yuan Zeng, Xiaodong Ying, Guanghui Dong, Jinxin Zhang, Jinyuan Zhao, Kangguang Lin, Xiaojiang Tang   +21 more
wiley   +1 more source