Results 201 to 210 of about 112,635 (314)

Efficacy of Retigabine in Treating Weakness in a Mouse Model of Hypokalemic Periodic Paralysis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Hypokalemic periodic paralysis (HypoKPP) is an ion channelopathy causing episodic skeletal muscle weakness triggered by hypokalemia. Reduced inward rectifier K+ (Kir) channel activity contributes to membrane depolarization and paralysis, suggesting that pharmacologic activation of muscle K+ channels may restore excitability ...
Kirsten Denman, Mark M. Rich
wiley   +1 more source

Health inequalities and trends in heart failure diagnosis in primary care in England, 2000-21: a national retrospective cohort data-linkage study. [PDF]

Lancet Prim Care
Lawson CA, Ali MR, McCann GP, Squire I, Zaccardi F, Rashid M, Barber K, Alaei Kalajahi R, Miller CA, Williams R, Clark AL, Petrie MC, Taylor CJ, Friday JM, Conrad N, Cleland JGF, Khunti K.   +16 more
europepmc   +1 more source

HPLC-DAD Profiling and Diuretic Effect of <i>Solanum elaeagnifolium</i> (Cav.) Aqueous Extract: A Combined Experimental and Computational Approach

Bouslamti Mohammed, Nouioura Ghizlane, Tbatou Widad, Mohamed Chebaibi, Abdulsalam Alhalmi, Najoua Soulo, Sulaiman Mohammed Alnasser, Fahad M. Alshabrmi, Amine Elbouzidi, Badiaâ Lyoussi, Benjelloun Ahmed Samir   +10 more
openalex   +1 more source

The Effects of Crude Drugs Using Diuretic on Horse Kidney (Na<SUP>+</SUP>+K<SUP>+</SUP>)-Adenosine Triphosphatase

, 1991
Kazuo Satoh, Ichiro Yasuda, Fumiko Nagai, Keiko Ushiyama, Kazuhisa Akiyama, Itsu Kano   +5 more
openalex   +2 more sources

Efficacy of a K+ Channel Agonist, XEN1101, For Preserving Contractility in Mouse Models of Hypokalemic Periodic Paralysis

Muscle &Nerve, EarlyView.
Pretreatment with an agonist of Kv7 potassium channels (XEN1101) protects the soleus muscle from a loss of force during a 2 mM K+ challenge, in a mouse model of hypokalemic periodic paralysis. ABSTRACT Introduction/Aims Effective management remains lacking for recurrent episodes of acute weakness in hypokalemic periodic paralysis (HypoPP).
Viktor Chanchykov, Sharon Iype, Marbella Quinonez, Fenfen Wu, Stephen Cannon   +4 more
wiley   +1 more source

Evaluation of the efficiency of at least 24-hour observation of transition to oral diuretic therapy before discharge on 30-day outcomes in acute heart failure patients: a comparative systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Alfehaid L, Tawfik Y, Alshibani M, Almutairi AR, Buckley LF, Al Yami MS.   +5 more
europepmc   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Clinical Parameters Associated with Achieving Negative Fluid Balance in Critically Ill Patients: A Retrospective Cohort Study. [PDF]

J Clin Med
Stavi D, Gal Oz A, Adi N, Dayan RR, Angel Y, Nevo A, Khoury N, Moshkovits I, Lichter Y, Wald R, Goder N.   +10 more
europepmc   +1 more source

Association between serum bicarbonate and low mid‐upper arm circumference in patients with non‐dialysis‐dependent chronic kidney disease: A cross‐sectional study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto, Shintaro Mandai, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Shotaro Naito, Eisei Sohara, Tatsuhiko Anzai, Kunihiko Takahashi, Wataru Akita, Akihito Ohta, Shinichi Uchida, Soichiro Iimori   +13 more
wiley   +1 more source

Extent and predictors of guideline-directed medical therapy optimization during cardiac rehabilitation in patients with heart failure. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Nicolas C, Girerd N, Duarte K, Huttin O, Djaballah K, Felloni J, Baudry G, Monzo L.   +7 more
europepmc   +1 more source