Results 31 to 40 of about 112,635 (314)

8‐Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background 8‐Aminoguanosine and 8‐aminoguanine are K+‐sparing natriuretics that increase glucose excretion. Most effects of 8‐aminoguanosine are due to its metabolism to 8‐aminoguanine.
Edwin K. Jackson, Zaichuan Mi, Thomas R. Kleyman, Dongmei Cheng   +3 more
doaj   +1 more source

Commentary on: “Chronic Use of Hydrochlorothiazide and Risk of Skin Cancer in Caucasian Adults: A PharmLines Initiative Inception Cohort Study

Acta Dermato-Venereologica, 2023
is missing (Correspondence)
Heber Rew Bright, Sujith J. Chandy, Renu George   +2 more
doaj   +1 more source

Correlation of diuretic therapy toward clinicaloutcomeof patients suffering from chronic kidney disease hospitalized in RSUP DR. M. Djamil Padang [PDF]

Pharmaciana, 2018
Kidney is one of the most important organs of the human body. The goal of diuretic therapy is to reduce edema in patients with impaired renal function. The therapy of diuretic is very important, because the therapy is effective to control of the volume ...
Fathnur Sani K, Armenia, Aina Fatkhil Haque   +2 more
doaj   +1 more source

Laser-Scribed Pencil Lead Electrodes for Amperometric Quantification of Indapamide

Chemosensors, 2023
Laser engraving is a convenient, fast, one-step, and environmentally friendly technique used to produce more conductive surfaces by local pyrolysis. The laser’s thermal treatment can also remove non-conductive materials from the electrode surfaces and ...
Thawan G. Oliveira, Irlan S. Lima, Wilson A. Ameku, Josué M. Gonçalves, Rodrigo S. Souza, Henrique E. Toma, Lúcio Angnes   +6 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Renal Transplantation and Hyperuricemia

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2020
Introduction: The adverse effects of hyperuricemia on renal function are of interest. Patients with a history of kidney transplantation are at the risk of hyperuricemia and its associated complications. Therefore, the identification and management of the
Sima Golmohammadi, Hamidreza Omrani, Zahra Ghorbani, Mahin Moradi   +3 more
doaj  

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

Arthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry, Bryant R. England, Harlan Sayles, Lindsay N. Helget, Maria Androsenko, Hongsheng Wu, Kaleb Michaud, Bridget Kramer, Jeff A. Newcomb, Mary T. Brophy, Anne Davis‐Karim, Ryan Ferguson, Michael H. Pillinger, Tuhina Neogi, Paul M. Palevsky, James R. O'Dell, Ted R. Mikuls   +16 more
wiley   +1 more source

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Arthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard, Cammie Tran, Hans G. Schneider, Flavia M. Cicuttini, Anita E. Wluka, Ego Seeman, Johannes T. Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P. Q. Clark, Daniel Clayton‐Chubb, Andrew M. Tonkin, Lawrence J. Beilin, Robyn L. Woods, John J. McNeil   +15 more
wiley   +1 more source

Comments on ALLHAT and doxazosin

Current Controlled Trials in Cardiovascular Medicine, 2001
This commentary has two purposes: to summarize the rationale, design and initial results of the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) trial; and to provide a history of the response to ALLHAT that led to a ...
Krakoff Lawrence R
doaj   +1 more source

POTASSIUM MONITORING IN HEART FAILURE PATIENTS RECEIVING COMBINED THERAPY OF CAPTOPRIL AND FUROSEMIDE

Folia Medica Indonesiana, 2017
In the treatment of heart failure is recommended the use of a combination of ACEI (captopril) with diuretics (furosemide), ACEI has the side effect of hyperkalemia 10-38% in hospitalized patients and 10% in outpatients, is increased in patients with ...
Hubby Hubby, Suharjono Suharjono, Zaenab Djafar   +2 more
doaj   +1 more source