Results 51 to 60 of about 232,806 (380)

8‐Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background 8‐Aminoguanosine and 8‐aminoguanine are K+‐sparing natriuretics that increase glucose excretion. Most effects of 8‐aminoguanosine are due to its metabolism to 8‐aminoguanine.
Edwin K. Jackson, Zaichuan Mi, Thomas R. Kleyman, Dongmei Cheng   +3 more
doaj   +1 more source

Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila [PDF]

, 2017
Multiple neuropeptides are known to regulate water and ion balance in Drosophila melanogaster. Several of these peptides also have other functions in physiology and behavior.
Davies, Shireen A., Marley, Richard, Nässel, Dick R., Zandawala, Meet   +3 more
core   +1 more source

Semaglutide and diuretic use in obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF-DM trials

European Heart Journal
Background and Aims In the STEP-HFpEF trial programme, treatment with semaglutide resulted in multiple beneficial effects in patients with obesity-related heart failure with preserved ejection fraction (HFpEF).
Sanjiv J. Shah, Kavita Sharma, Barry A. Borlaug, Javed Butler, M. Davies, D. Kitzman, Mark C. Petrie, Subodh Verma, Shachi Patel, Khaja M. Chinnakondepalli, M. N. Einfeldt, T. J. Jensen, Søren Rasmussen, Rabea Asleh, Tuvia Ben-Gal, M. Kosiborod   +15 more
semanticscholar   +1 more source

Diuretic Treatment in Heart Failure.

New England Journal of Medicine, 2017
This review discusses current pharmacologic principles of diuretic therapy, integrates data from recent research, and suggests evidence-based approaches to diuretic treatment in patients with heart failure.
D. Ellison, G. M. Felker
semanticscholar   +1 more source

Combination Therapy and Single-Modality Treatment for Acute Low-Tone Hearing Loss: A Meta-Analysis with Trial Sequential Analysis

Brain Sciences, 2022
Acute low-tone hearing loss (ALHL) is a common clinical disease and was first proposed by Abe in 1981 as sensorineural hearing loss confined to low frequencies.
Jing-Li Leong, Chih-Hao Chen, Chii-Yuan Huang, Hsiu-Lien Cheng, Yuan-Chia Chu, Chun-Yu Chang, Yen-Fu Cheng   +6 more
doaj   +1 more source

An in vivo study on the diuretic activity of Holarrhena antidysenterica [PDF]

, 2012
Holarrhena antidysenterica is used as diuretic in traditional medicine. The aim of this study was to evaluate the crude extract of H. antidysentrica seeds (Ha.Cr) and its fractions, n-hexane (Ha.Hx), n-butanol (Ha.Bu) and aqueous (Ha.Aq), for their ...
Bashir, Samra, Gilani, Anwar Hassan, Khan, Aslam   +2 more
core   +2 more sources

Interaction Between the Sodium‐Glucose–Linked Transporter 2 Inhibitor Dapagliflozin and the Loop Diuretic Bumetanide in Normal Human Subjects

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Dapagliflozin inhibits the sodium‐glucose–linked transporter 2 in the renal proximal tubule, thereby promoting glycosuria to reduce hyperglycemia in type 2 diabetes mellitus.
C. Wilcox, Wen-qing Shen, D. Boulton, B. Leslie, S. Griffen   +4 more
semanticscholar   +1 more source

POTASSIUM MONITORING IN HEART FAILURE PATIENTS RECEIVING COMBINED THERAPY OF CAPTOPRIL AND FUROSEMIDE

Folia Medica Indonesiana, 2017
In the treatment of heart failure is recommended the use of a combination of ACEI (captopril) with diuretics (furosemide), ACEI has the side effect of hyperkalemia 10-38% in hospitalized patients and 10% in outpatients, is increased in patients with ...
Hubby Hubby, Suharjono Suharjono, Zaenab Djafar   +2 more
doaj   +1 more source

Prolonged Administration of Rudgea viburnoides (Cham.) Benth. Prevents Impairment of Redox Status, Renal Dysfunction, and Cardiovascular Damage in 2K1C-Hypertensive Rats by Inhibiting ACE Activity and NO-GMPC Pathway Activation

Pharmaceutics, 2021
Rudgea viburnoides is widely found in the Brazilian Cerrado, and commonly used in Brazilian folk medicine. In this study, we evaluated the effects of prolonged administration of the aqueous extract from R.
Fernanda Viana Paulin, Rhanany Alan Calloi Palozi, Bethânia Rosa Lorençone, Arthur Ladeira Macedo, Lucas Pires Guarnier, Cleide Adriane Signor Tirloni, Paulo Vitor Moreira Romão, Arquimedes Gasparotto Junior, Denise Brentan Silva   +8 more
doaj   +1 more source

Relationship between antihypertensive medications and cognitive impairment: Part I. review of human studies and clinical trials [PDF]

, 2016
Purpose of review: There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHMs) and dementia risk ...
Anstey, KJ, Carlson, MC, Peters, J, Peters, R, Schuchman, M, Yasar, S   +5 more
core   +2 more sources