Results 51 to 60 of about 112,635 (314)

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

SYNTHESIS AND DIURETIC ACTIVITY OF 2-(5-(PHENOXYMETHYL)-4-R1-1,2,4-TRIAZOLE-3-YLTHIO)ACETIC ACIDS AND THEIR SALTS

open access: yesZaporožskij Medicinskij Žurnal, 2014
It is known that drugs based on the 1,2,4-triazole have a wide spectrum of biological activities. They are effective cardioprotectors, hepatoprotectors, anti-oxidants, which are widely used in cardiology practice.
Yu. N. Kucheryavyi   +2 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

Pharmacoepidemiology of Drug Exposure in Intubated and Non-Intubated Preterm Infants With Severe Bronchopulmonary Dysplasia

open access: yesFrontiers in Pharmacology, 2021
Background: Infants with severe bronchopulmonary dysplasia (BPD) are commonly treated with off-label drugs due to lack of approved therapies. To prioritize drugs for rigorous efficacy and safety testing, it is important to describe exposure patterns in ...
T. Lewis   +5 more
doaj   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

open access: yesAdvanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou   +14 more
wiley   +1 more source

Retraction: Diuretic effect of avocado (Persea americana Mill.) leaf extract on urine potassium and sodium levels in Sprague-Dawley rats

open access: yesCurrent Biomedicine, 2023
Announcement of manuscript withdrawal: The author has voluntarily submitted a request for retraction of the published manuscript. Based on these considerations, the editorial board decided to permanently withdraw this manuscript from circulation, both ...
Rini Madyastuti   +2 more
doaj   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

Bioaccessibility and Functional Food Potential of Equisetum telmateia Ehrh. Against Diabetes-Induced Kidney Disorders

open access: yesFoods
Various species from the genus Equisetum are recorded as food and folk medicine against both kidney complications and diabetes. Equisetum telmateia Ehrh. is documented as a folk remedy in Türkiye against several kidney disorders.
Timur Hakan Barak   +2 more
doaj   +1 more source

Comparative pharmacognosy of Pashanbhed

open access: yesJournal of Ayurveda and Integrative Medicine, 2014
Background: Pashanbhed is a commercially available diuretic and lithotropic drug, used to treat renal problems. It is a controversial name as it is assigned to various plants such as Bergenia ligulata, Kalanchoe pinnata, Coleus aromaticus and Rotula ...
Poonam Verma   +2 more
doaj   +1 more source

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