Results 91 to 100 of about 53,487 (288)

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Subcutaneous Furosemide Therapy for Chronic Management of Refractory Congestive Heart Failure in Dogs and Cats

Animals
Reduced efficacy of oral diuretics in the treatment of congestive heart failure (CHF) can be secondary to reduced enteral drug absorption. The aim of this study was to determine the efficacy of subcutaneous (SC) furosemide administration to control the ...
Sergio F. Lombardo, Heidi Ferasin, Luca Ferasin   +2 more
doaj   +1 more source

Use of serum osmolality to identify heart disease stage in dogs and relationship to mathematical chloride correction

Journal of Veterinary Internal Medicine, 2023
Background Heart failure‐associated hypochloremia can be depletional from diuretics or dilutional from water retention. Serum osmolality reflects water balance but has not been evaluated in dogs with heart disease.
Edward J. Daly, Autumn N. Harris, Darcy B. Adin   +2 more
doaj   +1 more source

Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain [PDF]

, 2017
There is accumulating evidence that bumetanide, which has been used over decades as a potent loop diuretic, also exerts effects on brain disorders, including autism, neonatal seizures, and epilepsy, which are not related to its effects on the kidney but ...
Erker, Thomas, Fedrowitz, Maren, Hampel, Philip, Kaczmarek, Edith, Löscher, Wolfgang, Römermann, Kerstin, Sweet, Douglas H., Töllner, Kathrin   +7 more
core   +2 more sources

Potent diuretic effects of prednisone in heart failure patients with refractory diuretic resistance [PDF]

Canadian Journal of Cardiology, 2007
Refractory congestive heart failure (CHF) with diuretic resistance is life-threatening and predicts a short life expectancy. Glucocorticoids have been proven to have potent diuretic effects in animal studies; however, their efficacy in CHF patients with diuretic resistance is not known.Thirteen CHF patients with significant volume overload and diuretic
Chao, Liu, Gang, Liu, Caixia, Zhou, Zhenguo, Ji, Yuzhi, Zhen, Kunshen, Liu   +5 more
openaire   +2 more sources

Elevated Hemoglobin Levels and Risk of ST‐Segment Elevation Myocardial Infarction in High‐Altitude Acute Coronary Syndrome: A Retrospective Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background High‐altitude populations typically exhibit elevated hemoglobin (Hb) levels due to chronic hypoxic exposure; however, the impact of this elevation on the risk of ST‐segment elevation myocardial infarction (STEMI) remains unclear. Existing evidence is primarily derived from low‐altitude populations and cannot be directly extrapolated
Jing Li, Lin‐Feng Liu, Gusang Lamu, Yang Jin, Gesang Gawa, Zhen‐Long Chang, Xiao‐Xia Liu, Zhen‐Zhong Yang, Gesang Luobu, Baima Lamu, Dawa Ciren   +10 more
wiley   +1 more source

Safety, Feasibility of Controllable Decrease of Vena Cava Pressure by Doraya Catheter in Heart Failure

JACC: Basic to Translational Science, 2023
Summary: Lowering elevated central venous pressure may reduce renal dysfunction in acute heart failure (AHF) patients. The Doraya catheter lowers renal venous pressure by creating a gradient in the inferior vena cava below the renal veins.
Robert Zymliński, MD, PhD, Jan Biegus, MD, PhD, Marc Vanderheyden, MD, Piotr Gajewski, MD, Riet Dierckx, MD, Jozef Bartunek, MD, Piotr Ponikowski, MD, PhD   +6 more
doaj   +1 more source

The prevalence of resistant arterial hypertension and secondary causes in a cohort of hypertensive patients: a single center experience [PDF]

, 2017
The prevalence of resistant hypertension (RHT) still remains unknown. Aim of the study was to investigate in a large cohort of hypertensive patients the prevalence of RHT, and to identify in these patients the secondary forms of arterial hypertension (SH)
Concistre, Antonio, Costi, Umberto, D'Ermo, Giuseppe, DE TOMA, Giorgio, DE VINCENTIS, Giuseppe, Iannucci, Gino, Letizia, Claudio, Lucia, Piernatale, Marinelli, Cristiano, Matteo, Galassi, Olmati, Federica, Pergolini, Mario Sergio, Petramala, Luigi, Tonnarini, Gian Franco   +13 more
core   +2 more sources

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

The role of urine sodium in acutely decompensated heart failure

International Journal of Cardiology: Heart & Vasculature
Background: Diuretic resistance is common and results in poor outcome. Spot urine sodium (UrNa) is suggested as a tool to tailor diuretics and improve efficacy of therapy. We prospectively evaluate the prevalence of diuretic resistance, predictors of low
Mick Hoen, Delian E Hofman, Bjorn H.A. Hompes, Lukas E.E. Peeters, Bart Langenveld, Roland R.J. van Kimmenade, Leon A.M. Frenken, Timo Lenderink, Hans-Peter Brunner-La Rocca, Sandra Sanders-Van Wijk   +9 more
doaj   +1 more source