Results 121 to 130 of about 53,487 (288)

Pathogenesis and Treatment of Refractory Oedema in Nephrotic Syndrome

European Medical Journal Urology, 2021
Oedema is a hallmark feature of nephrotic syndrome (NS) and can cause significant patient morbidity. The pathogenesis of oedema formation is complex and results from abnormalities in sodium retention, inter-play of neurohormonal factors, and changes in ...
Priyanka Jethwani, Namrata Krishnan
doaj  

Can we improve the treatment of congestion in heart failure? [PDF]

, 2011
INTRODUCTION: Dyspnoea and peripheral oedema, caused by fluid redistribution to the lungs and/or by fluid overload, are the main causes of hospitalization in patients with heart failure and are associated with poor outcomes.
Bettari L, Bugatti S, Carubelli V, Danesi R, Dei Cas L., Lazzarini V, Lombardi C, Metra M   +7 more
core   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]

, 2018
BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina, Graham, Delyth, Milligan, Graeme, Nicklin, Stuart A.   +3 more
core   +1 more source

P218 POTENTIAL ROLE OF NITROGLYCERIN FOR DIURETIC RESISTANCE IN ACUTE DECOMPENSATED HEART FAILURE: A PROOF OF CONCEPT STUDY [PDF]

, 2022
A Scollo, Simone Frea, Pier Paolo Bocchino, Filippo Angelini, G De Ferrari   +4 more
openalex   +1 more source

Deconvolution Methods to Link Multi‐Omics Data to Cell Type‐Specific Extracellular Vesicle Abundances

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) provide non‐invasive information on cellular health and disease. Yet, with the small size of EVs and more than 200 cell types contributing EVs to the extracellular fluids, it is challenging to determine whether changes in EV‐associated lipids, RNAs, and proteins occur because of differences in expression or cell ...
Iben Skov Jensen, Jannik Hjortshøj Larsen, Per Svenningsen   +2 more
wiley   +1 more source

DIURETIC RESISTANCE AS A GENERAL CLINICAL PROBLEM

Сеченовский вестник, 2010
Etiology, pathogenesis and treatment strategies in diuretic-resistant oedema are ...
N. A. Mukhin, V. V. Fomin, A. A. Pulin
doaj  

Using deep learning to assess the toxicological effects of sublethal exposure of a novel green pesticide in a stored‐product beetle

Pest Management Science, EarlyView.
This study employs an AI‐driven multidisciplinary approach to increase our understanding of the toxicological effects of sublethal concentrations of carlina oxide on Prostephanus truncatus. Sublethal exposure to the carlina oxide induced changes in motor patterns and thigmotaxis, highlighting its potential role in integrated pest management strategies.
Anita Casadei, Maria C. Boukouvala, Gianluca Manduca, Nickolas G. Kavallieratos, Filippo Maggi, Marta Ferrati, Eleonora Spinozzi, Cesare Stefanini, Antonio DeSimone, Donato Romano   +9 more
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Biomedical Research, A Tool to Address the Health Issues that Affect African Populations. [PDF]

, 2013
Traditionally, biomedical research endeavors in low to middle resources countries have focused on communicable diseases. However, data collected over the past 20 years by the World Health Organization (WHO) show a significant increase in the number of ...
Peprah, Emmanuel, Wonkam, Ambroise
core   +3 more sources