Results 161 to 170 of about 53,487 (288)

Diuretic Use in Heart Failure

open access: yesReviews in Cardiovascular Medicine
Heart failure (HF) is a major contributor to morbidity and mortality in the US and worldwide. HF is a complex condition characterized by the disruption of normal physiology and the activation of neurohumoral pathways, including the renin–angiotensin ...
George Nassar, Robert Jameson
doaj   +1 more source

Does furosemide decrease morbidity or mortality for patients with diastolic or systolic dysfunction? [PDF]

open access: yes, 2005
No large-scale randomized, placebo-controlled trials evaluate furosemide's effect on mortality and long-term morbidity in diastolic or systolic dysfunction.
Blackwell, Jean, Singh, Amrit
core  

Urine and Serum Albumin are Not Major Determinants of Diuretic Resistance in Heart Failure [PDF]

open access: bronze, 2016
Antonios Charokopos   +7 more
openalex   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

open access: yesExperimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó   +1 more
wiley   +1 more source

Effects of high‐intensity interval training on cardiac function in hypertensive and normotensive men: Effects of antihypertensive treatment

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise training is recommended for individuals with hypertension because it has been shown to lower blood pressure and reverse left ventricular concentric remodelling and mass. However, it is unclear how hypertensive individuals respond in comparison to normotensive individuals and to what extent medical treatment affects the outcome of ...
Mads Fischer   +8 more
wiley   +1 more source

Characterizing Alzheimer’s Disease and Related Dementia in a Hypertension Population Within the State of Florida Using Electronic Health Record–Based Data

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 751-762, March 2026.
Hypertension is a known modifiable risk factor for Alzheimer’s disease and related dementia (ADRD). However, it is unknown how variance in hypertension control, antihypertensive medications, and social determinants of health, such as social deprivation index (SDI), influence the risk of developing ADRD.
Eissa A. Jafari   +6 more
wiley   +1 more source

Decompensated Heart Failure and Diuretic Resistance

open access: yesJournal of the American College of Cardiology, 2006
The study by Costanzo et al. ([1][1]) confirmed an observation from my medical internship at The Peter Bent Brigham in 1952, but left an unanswered question. Doctor Samuel Levine had admitted a patient with severe edema of the feet and legs who was resistant to mercurial diuretics.
openaire   +1 more source

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

open access: yeseFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

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