Results 161 to 170 of about 53,487 (288)
Heart failure (HF) is a major contributor to morbidity and mortality in the US and worldwide. HF is a complex condition characterized by the disruption of normal physiology and the activation of neurohumoral pathways, including the renin–angiotensin ...
George Nassar, Robert Jameson
doaj +1 more source
Does furosemide decrease morbidity or mortality for patients with diastolic or systolic dysfunction? [PDF]
No large-scale randomized, placebo-controlled trials evaluate furosemide's effect on mortality and long-term morbidity in diastolic or systolic dysfunction.
Blackwell, Jean, Singh, Amrit
core
Urine and Serum Albumin are Not Major Determinants of Diuretic Resistance in Heart Failure [PDF]
Antonios Charokopos +7 more
openalex +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
[Diuretic resistance and heart failure: between congestion and kidney injury]. [PDF]
Morejón Barragán P.
europepmc +1 more source
Abstract Exercise training is recommended for individuals with hypertension because it has been shown to lower blood pressure and reverse left ventricular concentric remodelling and mass. However, it is unclear how hypertensive individuals respond in comparison to normotensive individuals and to what extent medical treatment affects the outcome of ...
Mads Fischer +8 more
wiley +1 more source
Hypertension is a known modifiable risk factor for Alzheimer’s disease and related dementia (ADRD). However, it is unknown how variance in hypertension control, antihypertensive medications, and social determinants of health, such as social deprivation index (SDI), influence the risk of developing ADRD.
Eissa A. Jafari +6 more
wiley +1 more source
Decompensated Heart Failure and Diuretic Resistance
The study by Costanzo et al. ([1][1]) confirmed an observation from my medical internship at The Peter Bent Brigham in 1952, but left an unanswered question. Doctor Samuel Levine had admitted a patient with severe edema of the feet and legs who was resistant to mercurial diuretics.
openaire +1 more source
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley +1 more source
Plasma Renin Activity (PRA) Predicts Diuretic Resistance in Acute Heart Failure Patients: An Ancillary Study of the Diuretic Optimization Strategies Evaluation in Acute Heart Failure (DOSE-AHF) [PDF]
Tomohito Ohtani +5 more
openalex +1 more source

