Results 71 to 80 of about 53,487 (288)

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

Diuretic treatment of resistant hypertension. [PDF]

BMJ, 1980
In patients with hypertension resistant to three or four drugs including a thiazide diuretic substitution of frusemide for the thiazide, or the addition of spironolactone, produced significant reductions in blood pressure and body weight. The response did not depend on the presence of overt fluid retention, renal impairment, or the use of ...
L E, Ramsay, J H, Silas, S, Freestone
openaire   +2 more sources

Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila [PDF]

, 2017
Multiple neuropeptides are known to regulate water and ion balance in Drosophila melanogaster. Several of these peptides also have other functions in physiology and behavior.
Davies, Shireen A., Marley, Richard, Nässel, Dick R., Zandawala, Meet   +3 more
core   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]

, 2010
Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO, Rossi C, RUBATTU, Speranza Donatella, SAVOIA, Carmine, VOLPE, Massimo   +4 more
core   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza, Abdelgadir, Abdu-Aguye, Abdulrazaq, Abubakar, Adebayo, Adedoyin, Adelusi, Ademuyiwa, Adeneye, Adeneye, Adeneye, Adeneye, Aderibigbe, Adeyemi, Adisa, Adler, Agbor, Agnaniet, Agunbiabe, Agyare, Ajaiyeoba, Ajaiyoeba, Ajao, Ajayi, Akah, Akash, Akinloye, Akpanyung, Aladodo, Alaribe, Amole, Anaduaka, Anosike, Anowi, Anowi, Antia, Anyanwu, Apers, Areola, Arthur, Asadu, Asha, Ashraf, Asolkar, Assob, Asuquo, Atangwho, Atawodi, Atawodi, Aw, Awah, Awe, Aziba, B. Bading Taika, Balasubramanian, Bamisaye, Bapna, Bardi, Bayan, Bella, Ben-Chioma, Bera, Biney, Bisong, Brantley, Calapai, Campbell, Campbell-Tofte, Capasso, Chika, Chokshi, Chris-Ozoko, Coolborn, Coria-Téllez, Da-Costa-Rocha, Dadzeasah, Dahake, Das, Dhanabalan, Djeussi, Djimeli, Djomeni, Djomeni Dzeufiet, Effiong, Effiong, Effo, Eidi, Ejike, El-Demerdash, Elufioye, Elumalai, Eluwa, Eneh, Erharuyi, Erhirhie, Eteng, Etuk, Ewenighi, Ewere, Eyong, Eze, Ezeasor, Ezejindu, Ezejiofor, Ezeokeke, Ezike, Ezuruike, Fang-Chui, Farzaei, Fernand, Ferreira, Feuya Tchouya, Feuya Tchouya, Fongang, Fred-Jaiyesimi, Gandhare, Ganesh, Gbadegesin, Gboeloh, Gemede, Ghani, Ghiware, Gomez-Flores, Gondi, Goutarel, Gupta, Gutierrez, H.P. Bourobou Bourobou, Halim, Hamzah, Hansen, Helfer, Hossain, Houghton, Houël, Huang, Huang, Husain, Husin, Ibibia, Igbe, Igboasoiyi, Ilodigwe, Ilodigwe, Ilusanya, Inya-Agha, Iroanya, Irondi, Irondi, Ishola, Iwu, Iyamah, Jawonisi, Juárez-Rojop, Juárez-Rojop, Kadima, Kaiser, Kamagate, Kamboj, Karimi, Karioti, Kathirvel, Kazeem, Kazeem, Kengni, Kengni, Khodabakhsh, Kolawole, Kouakou, Koudou, Kouitcheu Mabeku, Krishna, Kubilienė, Kuete, Kuete, Kuete, Kulkarni, Kumar, Kumar, Kumar, Kupchan, L. Lione, L.S. MacKenzie, Lakshmi, Lamidi, Lawal, Lawal, Laxane, Lee, Li, Lima, Ludvik, Ludvik, Luka, M. Bouckandou, Mabeku, Madingou, Madingou, Malviya, Manga, Maniyar, Manjur, Manvitha, Mathur, Maurya, Mačiulaitis, Mbiantcha, Mebale, Mengome, Midawa, Miranda-Osorio, Mishra, Miura, Mohamed, Mohammed, Mohammed, Mohammed, Mohammed, Momoh, Montasser, Muhammad, Muhammad, Muhammad, Muhammad, Muttaka, Nabukenya, Nakavuma, Naseri, Naskar, Navghare, Ndam, Nessa, Ngoc, Ngondi, Ngondi, Ngueguim, Ngueguim, Nishimura, Niyonzima, Nkono Ya Nkono, Nkono Ya Nkono, Ntyonga-Pono, Nwamarah, Nweze, Nwodo, Nwokocha, Nyunaï, Nyunaï, N’doua, N’guessan, N’Guessan, Obiang, Obiudu, Ocho-Anin Atchibri, Oduola, Oduola, Ofusori, Ogbonnia, Ogunrinola, Ojewole, Ojewole, Ojewunmi, Ojewunmi, Ojiako, Okeke, Okokon, Okokon, Okokon, Okolie, Okolo, Okonkwo, Olajide, Olaleye, Olatokunboh, Olivier, Olowu, Olubomehin, Ombra, Omodamiro, Omonkhua, Ong, Onyekwe, Osabede, Osadebe, Osigwe, Ouédraogo, Oyewusi j, Ozsoy-Sacan, Padilla-Camberos, Palaksha, Panda, Panda, Parle, Passoni, Patel, Patil, Ping, Pochapski, Pour, Pérez, Rajesh, Raji, Rauf, Ravi, Renjith, Rong, Rosemary, Roy, Sabitha, Sagnia, Santas, Satyaprakash, Saxena, Seung, Shah, Sharma, Sharma, Sharma, Shittu, Silva, Singh, Singh, Sio, Somova, Souza, Sowemimo, Sudhakar, Sule, Sunday, Sunday, Suryawanshi, Sutar, Swargiary, Swathi, Taj Eldin, Talreja, Tan Paul, Tanayen, Tchamadeau, Teugwa, Thongsom, Titanji, Tjeck, Togola, Toma, Toma, Trabelsi, Uchechi, Ufelle, Umoh, Vannamalar, Varghese, Varghese, Vashishtha, Verma, Verma, Vijayalakshmi, Vikram, Vliet, Wang, Wang, Wauthoz, Woode, Yakubu, Yasir, Yeap, Yessoufou, Yokozawa, Yousuf, Yu, Zakiah, Zhang, Zhao, Zheng   +374 more
core   +4 more sources

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

Ultrafiltration for acute decompensated cardiac failure: A systematic review and meta-analysis [PDF]

, 2016
Background Ultrafiltration is a method used to achieve diuresis in acute decompensated heart failure (ADHF) when there is diuretic resistance, but its efficacy in other settings is unclear. We therefore conducted a systematic review and meta-analysis to
Ahmed, F, Cunnington, C, Davies, S, Kwok, CS, Mamas, M, Patwala, A, Rushton, CA, Satchithananda, D, Wong, CW   +8 more
core   +2 more sources

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source