Results 101 to 110 of about 8,359,193 (315)

Isoform- and Cell-Specific Function of Tyrosine Decarboxylase in the Drosophila Malpighian Tubule [PDF]

, 2009
The biogenic amine tyramine (TA) is a potent diuretic factor when applied to the Malpighian tubule (MT) of Drosophila melanogaster, stimulating both urine production and transepithelial chloride conductance.
Blumenthal, Edward M
core   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

First experience with Tolvaptan for the treatment of neonates and infants with capillary leak syndrome after cardiac surgery

BMC Pediatrics, 2019
Background Postoperative fluid management in critically ill neonates and infants with capillary leak syndrome (CLS) and extensive volume overload after cardiac surgery on cardiopulmonary bypass is challenging.
Anne Kerling, Okan Toka, André Rüffer, Hanna Müller, Sheeraz Habash, Christel Weiss, Sven Dittrich, Julia Moosmann   +7 more
doaj   +1 more source

Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: a pharmacogenomics study from the CHARGE consortium [PDF]

, 2015
Background Hypertension is a major risk factor for a spectrum of cardiovascular diseases (CVD), including myocardial infarction, sudden death, and stroke.
Arnett, Donna, Avery, Christy L., Bis, Joshua C., Boerwinkle, Eric, Brody, Jennifer A., Buckley, Brendan M., Chen, Yii-Der Ida, Cummings, Steven R., Cupples, L. Adrienne, Davis, Barry R., de Craen, Anton J. M., Demissie, Serkalem, Eckfeldt, John H., Evans, Daniel S., Ford, Ian, Franco, Oscar H., Gudnason, Vilmundur, Harris, Tamara B., Heckbert, Susan R., Hofman, Albert, Ikram, M. Arfan, Irvin, Ryan, Jukema, J. Wouter, Krijthe, Bouwe P., Lange, Leslie A., Launer, Lenore J., Li, Xiaohui, Liu, Yongmei, Lumley, Thomas, Musani, Solomon K., Post, Wendy, Psaty, Bruce M., Quibrera, P. Miguel, Rotter, Jerome I., Sattar, Naveed, Sitlani, Colleen, Slagboom, P. Eline, Smith, Albert Vernon, Smith, Nicholas L., Sotoodehnia, Nona, Stott, David J., Stricker, Bruno H., Stürmer, Til, Sun, Fangui, Taylor, Herman A., Taylor, Kent D., Tranah, Gregory J., Trompet, Stella, Uitterlinden, Andre G., Vasan, Ramachandran S., Westendorp, Rudi, Whitsel, Eric A., Wiggins, Kerri L., Wilson, James G.   +53 more
core   +4 more sources

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Effect of Hypertension on Outcomes of High-Risk Patients After BCG-Treated Bladder Cancer [PDF]

, 2015
Immunotherapy with Bacillus Calmette Guerin (BCG) is the most efficacious treatment for high-risk bladder cancer (BC) (Ta/T1 or carcinoma in situ) to reduce the risk of recurrence.
Alberto, Bovo, Alessandro, Crestani, DAL MORO, Fabrizio, Marina P., Gardiman, Roberto, Vettor, Zattoni, Filiberto   +5 more
core   +1 more source

Understanding Engagement Experiences in an Adapted Digital Cognitive Behavioral Intervention for Lower‐Income Adults With Eating Disorders With Binge Eating and/or Purging: A Qualitative Analysis of Barriers and Facilitators

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study explored the experiences of lower‐income adults in accessing and engaging with an adapted digital guided self‐help cognitive behavioral intervention for binge and/or purge‐type eating disorders. This study sought to inform future adaptation of evidence‐based eating disorder interventions to improve accessibility ...
Kimberly Yu, Siena Vendlinski, Hannah Beck, Nancy Jacquelyn Pérez‐Flores, Catherine R. Drury, Ellen E. Fitzsimmons‐Craft, Erin C. Accurso   +6 more
wiley   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

A 2018 overview of diuretic resistance in heart failure

Revista Portuguesa de Cardiologia, 2018
Heart failure is a disease with high direct and indirect costs. Current treatment includes drugs that alter disease progression and drugs that to improve symptoms.
Sofia Isabel Jardim, Luís Ramos dos Santos, Inês Araújo, Filipa Marques, Patrícia Branco, Augusta Gaspar, Cândida Fonseca   +6 more
doaj   +1 more source

Mitochondrial haplogroup association with fasting glucose response in African Americans treated with a thiazide diuretic [PDF]

, 2022
Bré Minniefield, Nicole D. Armstrong, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Scott W. Ballinger, Zechen Chong, Stella Aslibekyan, Donna K. Arnett, Marguerite R. Irvin   +8 more
openalex   +3 more sources