Results 51 to 60 of about 8,359,193 (315)

Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo [PDF]

, 2013
Cyclic AMP (cAMP) is a ubiquitous second messenger that regulates a variety of essential processes in diverse cell types, functioning via cAMP-dependent effectors such as protein kinase A (PKA) and/or exchange proteins directly activated by cAMP (EPAC ...
Akbari, Baillie, Beyenbach, Beyenbach, Bos, Bos, Bos, Brand, Börner, Cabrero, Chepurny, Coast, Coast, Coast, Coast, Dames, Davies, Day, de Rooij, Dow, Dow, Dow, Dow, Enserink, Evans, Gloerich, Guo, Hallows, Hector, Iijima–Ando, Johnson, Johnson, Kalderon, Kandel, Kaufmann, Kaupp, Kerr, Laroche–Joubert, MacPherson, O'Donnell, O'Donnell, Parks, Pastor–Soler, Pastor–Soler, Poulsen, Radford, Rein, Rosay, Ryu, Ryu, Schröder–Lang, Stierl, Stokman, Sözen, Terhzaz, Terhzaz, Torrie, Weissenberger, Wong, Zaccolo, Zaccolo   +60 more
core   +1 more source

Determinants and impact of the natriuretic response to diuretic therapy in heart failure with reduced ejection fraction and volume overload

Acta Cardiologica, 2015
Frederik H. Verbrugge, Matthias Dupont, Philippe B. Bertrand, Petra Nijst, Joris Penders, Joseph Dens, David Verhaert, Pieter Vandervoort, W.H. Wilson Tang, Wilfried Müllens   +9 more
openalex   +3 more sources

Protocolized Natriuresis-Guided Decongestion Improves Diuretic Response: The Multicenter ENACT-HF Study

Circulation: Heart Failure
Background: The use of urinary sodium to guide diuretics in acute heart failure is recommended by experts and the most recent European Society of Cardiology guidelines. However, there are limited data to support this recommendation.
Jeroen Dauw, K. Charaya, M. Lelonek, I. Zegri-Reiriz, Samer Nasr, Cynthia P Paredes-Paucar, A. Borbély, Fatih Erdal, R. Benkouar, M. Cobo-Marcos, G. Barge-Caballero, Varghese George, Cornelia Zara, Noel T Ross, Diane Barker, A. Lekhakul, S. Frea, A. Ghazi, D. Knappe, N. Doghmi, Milka Klincheva, I. Fialho, V. Bovolo, Hajo Findeisen, I. Alhaddad, A. Galluzzo, R. de la Espriella, R. Tabbalat, Ò. Miró, Jagdeep S Singh, P. Nijst, M. Dupont, Pieter Martens, Wilfried Mullens   +33 more
semanticscholar   +1 more source

Baseline characteristics and enrichment results from the SONAR trial [PDF]

, 2018
Aim: The SONAR trial uses an enrichment design based on the individual response to the selective endothelin receptor antagonist atrasentan on efficacy (the degree of the individual response in the urinary albumin‐to‐creatinine ratio [UACR]) and safety/
Andress, Dennis L., Bakris, George, Brennan, John J., Correa-Rotter, Ricardo, de Zeeuw, Dick, Heerspink, Hiddo J.L., Hou, Fan Fan, Kitzman, Dalane W., Kohan, Donald, Makino, Hirofumi, McMurray, John, Parving, Hans-Henrik, Perkovic, Vlado, Tobe, Sheldon, Wigderson, Melissa, Yi, Tingting   +15 more
core   +3 more sources

Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review [PDF]

, 2016
© The Author(s) 2016Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use.
Farag, Mohamed, Gorog, Diana A, Shoaib, Ahmad   +2 more
core   +2 more sources

Diuretic treatment using the RenalGuard® system in patients hospitalized due to acute decompensated heart failure and characterization of the profile of patients with good and poor response to treatment — preliminary study

Cardiology Journal
BACKGROUND: The aim of the study was to analyze the potential relationship between the diuretic response, the clinical profile and the concentrations of selected biochemical markers and to identify a group of patients who will benefit from a new form of ...
Paweł Siwołowski, Piotr Gajewski, Mateusz Sokolski, Robert Zymliński, Mateusz Guzik, Joanna Szachniewicz, Piotr Ponikowski   +6 more
doaj   +1 more source

Heat shock proteins and the cellular response to osmotic stress [PDF]

, 2000
In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Beck, Franz-X., Grünbein, Rita, Lugmayr, Karin, Neuhofer, Wolfgang   +3 more
core   +1 more source

The role of diuretic hormones (DHs) and their receptors in Drosophila

BMB Reports, 2023
Maintaining internal homeostasis and regulating innate behaviors are essential for animal survival. In various animal species, a highly conserved neuroendocrine system integrates sensory inputs and regulates physiological responses to environmental and ...
Gah-Hee Lee, Heejin Jang, Yangkyun Oh
semanticscholar   +1 more source

Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii [PDF]

, 2017
Background: Neuropeptides are central to the regulation of physiological, and behavioural processes in insects, directly impacting cold and desiccation survival.
Al-Anzi, Asplen, Atallah, Audsley, Cabrero, Cabrero, Cannell, Choi, Chown, Cini, Coast, Coast, Condon, Dalton, David, Davies, Denlinger, Dow, Dow, Enriquez, Gerken, Gibbs, Goodhue, Hadley, Halberg, Hoffmann, Hoffmann, Huey, Jakobs, Jakobs, Jensen, Kacar, Kahsai, Kang, Kean, Kelty, Li, Matsumura, Matzkin, McWilliam, Nässel, O'Donnell, Plantamp, Poyet, Rajpurohit, Ryan, Schiffer, Schooley, Shearer, Sinclair, Sinclair, Sinclair, Stephens, Sørensen, Taghert, Telonis-Scott, Terblanche, Terhzaz, Terhzaz, Terhzaz, Tochen, Toxopeus, Wallingford, Yeoh   +63 more
core   +2 more sources

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

Arthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry, Bryant R. England, Harlan Sayles, Lindsay N. Helget, Maria Androsenko, Hongsheng Wu, Kaleb Michaud, Bridget Kramer, Jeff A. Newcomb, Mary T. Brophy, Anne Davis‐Karim, Ryan Ferguson, Michael H. Pillinger, Tuhina Neogi, Paul M. Palevsky, James R. O'Dell, Ted R. Mikuls   +16 more
wiley   +1 more source