Results 141 to 150 of about 2,102,359 (301)

Metabolite Profiles and Antioxidant Activity of Dendrobium catenatum Under Simulated Wild Cultivation

Food Safety and Health, EarlyView.
Dendrobium catenatum grown under simulated wild cultivation showed significantly higher flavonoids and stilbenes, leading to enhanced antioxidant activity in both leaves and stems compared to facility‐grown plants. Integrated metabolomics, antioxidant assays, and network pharmacology identified Denbinobin as a key multi‐target antioxidant compound ...
Chuyun Guan, Yixin Tang, Qiaoxian Yu, Yanghui Shen, Ying Shi, Pan Wang, Jinping Si, Jingjing Liu   +7 more
wiley   +1 more source

Optimization of moisture content and application rate of hay preservative during high‐moisture alfalfa hay baling in northwestern China

Grassland Research, EarlyView.
Abstract Background Leaf shatter during low‐moisture baling and mold proliferation under high‐moisture conditions pose major challenges in alfalfa hay production. A proprietary propionic acid‐based hay preservative product, LZP, effectively inhibits microbial reproduction in high‐moisture alfalfa bales; however, its optimal moisture thresholds and ...
Zulin Yuan, Fuhou Li, Jing Li, Dongmei Xu, Samaila Usman, Xusheng Guo, Yingwen Yu   +6 more
wiley   +1 more source

Disturbance from restoration reseeding is associated with short‐term topsoil carbon loss and alters soil bacterial communities and functions in degraded alpine meadows of the Qinghai–Xizang Plateau

Grassland Research, EarlyView.
Restoration reseeding of degraded alpine meadows increased aboveground vegetation but was associated with short‐term topsoil carbon loss, coinciding with a microbial strategy shift from resident carbon‐preserving to carbon‐spending bacterial guilds. Abstract Background Restoration of degraded ecosystems is widely promoted as a nature‐based solution ...
Long‐Tao Zhu, Wen‐Min Shi, Guang‐Peng Qu, Xu Yin, Yong‐Kang Zhang, Ying‐Jie Sun, Zhen Luo, Wei Li, Chun‐Ping Zhang, Jie‐Jun Xi   +9 more
wiley   +1 more source

Dynamic Physician Rostering in Emergency Departments: Managing Reentrant Patient Flows to Meet Excess Wait Time Targets

Health Care Science, EarlyView.
We develop a patient flow model that integrates return loops and formulate a risk‐aware physician rostering framework designed to strictly enforce excess wait time targets, for example, tail probability of delay (TPoD) service levels. We employ a simulation‐based iterative staffing approach (ISA) to determine the optimal number of physicians required ...
Xu Dai, Peng Gao, Xiaolei Xie
wiley   +1 more source

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source

Maternal overweight and obesity during pregnancy and sex‐dependent dysregulation of the materno‐fetal stress axis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Maternal obesity and excess gestational weight gain (GWG) are linked to adverse perinatal outcomes, potentially via disruption of the maternal–fetal stress axis. Placental HSD11B2 protects the fetus from excess glucocorticoids and may influence fetal programming during maternal metabolic stress.
Thorsten Braun, Marie Hofmann, Rebecca Rancourt, Julia Sommer, Alexandra Kühn, Loreen Ehrlich, Thomas Ziska, Kerstin Melchior, Karen Schellong, Wolfgang Henrich, Sonja Entringer, Katherine Margaret Kennedy, Andreas Plagemann, Deborah Magdalena Sloboda   +13 more
wiley   +1 more source

Polymorphic STRs represent unique genetic signals beyond SNPs associated with climate adaptation in Marchantia polymorpha

iMetaOmics, EarlyView.
Natural populations of Marchantia polymorpha sampled across contrasting climatic regions show clear geographic differentiation between Europe and Japan based on polymorphic short tandem repeat (STR) variation. Genome‐wide association (GWAS) analyses identified pSTR loci whose repeat‐length variation tracks temperature‐related WorldClim variables.
Shuangyang Wu, Shenghan Gao, Sen Wang, Martin Lascoux, Hao Yu   +4 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Diurnal intraocular pressure variation in pseudoexfoliation syndrome

, 2004
PURPOSE. To describe and compare the diurnal intraocular pressure (IOP) variation in patients with pseudoexfoliation syndrome (PXS) and normal ...
Caglar, Y, Yuksel, NURŞEN, Altintas, O, Karabas, VL   +3 more
core   +1 more source