Results 231 to 240 of about 224,273 (307)

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

UCanWBGT: urban street canyon heat stress calculation for weather and climate models

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
This work introduces UCanWBGT, a new model to calculate wet‐bulb globe temperature in an urban environment, suitable for use with weather and climate model data. We present the model, then verify its performance against observations made in the streets of Paris during heatwave conditions.
Jonathan K. P. Shonk   +4 more
wiley   +1 more source

Dynamics and model representation of two contrasting extreme precipitation events in the Sahel

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Hovmöller diagrams of the two investigated extreme precipitation events in Mali are shown for (i) IMERG observations, and ICOsahedral Nonhydrostatic model (ICON) runs with parameterization of explicit convection (ii) enabled and (iii) disabled. This work highlights that the commonly perceived benefit of using explicit convection in a state‐of‐the‐art ...
Souleymane Sanogo   +4 more
wiley   +1 more source

The role of soil moisture in the inland penetration of Indian monsoon low‐pressure systems

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We use the Advanced Weather Research and Forecasting model to examine the role of soil moisture in the inland penetration of Indian monsoon low‐pressure systems (LPSs). We find that LPSs penetrate deeply into India despite a dry land surface; however, their inland penetration is adversely affected when there is a reduction in the total surface heat ...
Akshay Deoras   +2 more
wiley   +1 more source

Diurnal variation in variables related to cognitive performance: a systematic review. [PDF]

open access: yesSleep Breath
Munnilari M   +8 more
europepmc   +1 more source

Thermodynamic and microphysical properties of summertime marine fog observed from Sable Island

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Atmospheric profiling and near‐surface fog and visibility measurements revealed synoptic‐scale forcing as the dominant factor in fog formation over Sable Island, with deep fog layers under low‐pressure systems and shallow fog layers under high‐pressure systems.
Kelsey Rowe   +7 more
wiley   +1 more source

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