Arresting an Unusual Amide Tautomer Using Divalent Cations
Ion-specific effects on peptides and proteins are key to biomolecular structure and stability. The subtle roles of the cations are far less understood, compared to the pronounced effects of the anions on proteins.
Hyejin Kwon (1278540) +5 more
core +2 more sources
Structural Insights into the Osteopontin-Aptamer Complex by Molecular Dynamics Simulations
Osteopontin is an intrinsically disordered protein involved in tissue remodeling. As a biomarker for pathological hypertrophy and fibrosis, the protein is targeted by an RNA aptamer.
Giovanni La Penna, Riccardo Chelli
doaj +1 more source
Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C. [PDF]
Cardiac troponin C (cTnC) is a key effector in cardiac muscle excitation-contraction coupling as the Ca2+ sensing subunit responsible for controlling contraction. In this study, we generated several FRET sensors for divalent cations based on cTnC flanked
Myriam A Badr +3 more
doaj +1 more source
Boron adsorption in semiarid Mediterranean soils under the influence of background electrolytes [PDF]
BACKGROUND AND OBJECTIVES: Boron is a micronutrient of high importance, both for plant development and normal growth. The range between boron deficiency and toxicity is very narrow, which makes boron unique among the essential micronutrients.
S. Fatnassi +4 more
doaj +1 more source
The regulation of integrin function by divalent cations [PDF]
Integrins are a family of α/β heterodimeric adhesion metalloprotein receptors and their functions are highly dependent on and regulated by different divalent cations. Recently advanced studies have revolutionized our perception of integrin metal ion-binding sites and their specific functions.
Kun, Zhang, JianFeng, Chen
openaire +2 more sources
Effect of charge balancing cations on the viscoelastic and thermal properties of welan
Welan is a branched polymer in the gellan family of polysaccharides. It has good compatibility with divalent calcium ions with a potential use in cementing applications.
Chengrong Wen +5 more
doaj +1 more source
In this data article we have provided evidence for the negative influence of divalent cations on (−)‐epigallocatechin-3-gallate (EGCG)-mediated inhibition of matrix metalloproteinase-2 (MMP-2) activity in cell-free experiments.
Gauri Deb, Sahil Batra, Anil M. Limaye
doaj +1 more source
The binding of divalent cations to myosin
Centrifuge transport, equilibrium dialysis, and electron paramagnetic resonance studies on the binding of Mn2+ to myosin revealed two sets of noninteracting binding sites which are characterized at low ionic strength (0.016 M KCl) by affinity constants of 10(6) M-1 (Class I) and 10(3) M-1 (Class II), respectively.
M C, Beinfeld +3 more
openaire +2 more sources
Charge Shielding of PIP2 by Cations Regulates Enzyme Activity of Phospholipase C.
Hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) of the plasma membrane by phospholipase C (PLC) generates two critical second messengers, inositol-1,4,5-trisphosphate and diacylglycerol.
Jong Bae Seo +4 more
doaj +1 more source
3D printing of a bio-based ink made of cross-linked cellulose nanofibrils with various metal cations
In this work, we present an approach to cross-link cellulose nanofibrils (CNFs) with various metallic cations (Fe3+, Al3+, Ca2+, and Mg2+) to produce inks suitable for three-dimensional (3D) printing application. The printability of each hydrogel ink was
J. Benedikt Mietner +4 more
doaj +1 more source

