Results 191 to 200 of about 1,557,512 (335)

Energy-dissipative adaptive-step L1 discretisation for the Caputo time-fractional incompressible magnetohydrodynamic system. [PDF]

Sci Rep
Abidin MZ.
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Relative-to-human benchmark Cognitive Divergence and semantic comprehensibility in Chinese-Uyghur LLM translation. [PDF]

Front Psychol
Zuo J, Wang Y, Yibulayin X.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Schizothoracinae in Plateau River Networks: Drainage History, Polyploid Genome Evolution, Multi-Omics Evidence Chains, and Conservation Units. [PDF]

Animals (Basel)
Cao Y, Wang N, Hu Q, Zhu X.
europepmc   +1 more source

Divergences au sein de la zone euro : la centrifugeuse ?

, 2017
Jacques Le Cacheux
openalex   +1 more source

An optimization approach for mapping and measuring the divergence and correspondence between paths [PDF]

, 2015
Shane T. Mueller, Brandon S. Perelman, Elizabeth S. Veinott   +2 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Mitogenomes reveal the timing and distribution of divergence events among trans-Beringian birds. [PDF]

PeerJ
Collier KA, Glenn TC, Takebayashi N, Hickerson MJ, Winker K.   +4 more
europepmc   +1 more source

Intraspecific divergences and phylogeography of Panzerina lanata (Lamiaceae) in Northwest China

, 2018
Yanfen Zhao, Hongxiang Zhang, Bo‐Rong Pan, Mingli Zhang   +3 more
openalex   +1 more source