Results 121 to 130 of about 2,518,110 (330)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Morphological divergence rate tests for natural selection: uncertainty of parameter estimation and robustness of results

open access: yesGenetics and Molecular Biology, 2005
In this study, we used a combination of geometric morphometric and evolutionary genetics methods for the inference of possible mechanisms of evolutionary divergence.
Leandro R. Monteiro, José L. Gomes-Jr
doaj   +1 more source

Bayesian Estimation of Species Divergence Times Using Correlated Quantitative Characters

open access: yesbioRxiv, 2018
Discrete morphological data have been widely used to study species evolution, but the use of quantitative (or continuous) morphological characters is less common.
Sandra Álvarez-Carretero   +3 more
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Calibration points used for the estimation of the divergence times.

open access: yes, 2016
Calibration points used for the estimation of the divergence times.
Adam Slipinksi (2657599)   +4 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Calibration points for the divergence time estimation using MCMCTREE.

open access: yes, 2013
Calibration points for the divergence time estimation using MCMCTREE.
Mutsumi Nishida (38197)   +13 more
core   +1 more source

A simulation study of semiparametric estimation in copula models based on minimum Alpha-Divergence

open access: yes, 2020
The purpose of this paper is to introduce two semiparametric methods for the estimation of copula parameter. These methods are based on minimum Alpha-Divergence between a non-parametric estimation of copula density using local likelihood probit ...
Mohammadi, Morteza   +2 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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